Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8672242 | 0.83 | APOBEC3A (0.37) | ALOX5APMEN1KMT2AHTTKDM4E | |
| SCHEMBL8671760 | 0.81 | TDP1 (0.45) | MEN1KMT2AHTTKDM4EALDH1A1 | |
| SCHEMBL8674069 | 0.81 | MEN1 (0.34) | ALOX5APMEN1KMT2AHTTKDM4E | |
| SCHEMBL18057354 | 0.73 | CASP3 (0.38) | ALOX5APMEN1KMT2AHTTKDM4E | |
| SCHEMBL20335460 | 0.72 | L3MBTL1 (0.43) | MEN1KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL9730644 | 0.70 | KCNJ5 (0.37) | ALOX5APKDM4EALDH1A1POLBMAPT | |
| SCHEMBL11873901 | 0.69 | TDP1 (0.62) | MEN1KMT2ABACE1HTTKDM4E | |
| SCHEMBL4364664 | 0.68 | ADORA2A (0.42) | ALOX5APKMT2AHTTKDM4EALDH1A1 | |
| SCHEMBL25323103 | 0.66 | BACE1 (0.46) | BACE1HTTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL15448564 | 0.66 | BACE1 (0.46) | MEN1KMT2ABACE1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830903-A | ANTIULCER AGENTS | ALKALOIDA CHEMICAL CO., LTD. (HU) | 1998-11-03 | — | — | US | disclosed |
| EP-0643579-A1 | TRIAZOLE SUBSTITUTED QUINOLINE DERIVATIVES | ALKALOIDA VEGYESZETI GYAR RT (HU) | 1995-03-22 | — | — | EP | disclosed |
| WO-1994022413-A2 | TRIAZOLE SUBSTITUTED QUINOLINE DERIVATIVES | ALKALOIDA VEGYÉSZETI GYÁR RT. (HU) | 1994-10-13 | — | — | WO | disclosed |