Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 11/20 | 0.50 |
| ▸ | CES1 | P23141 | 10/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9905530 | 1.00 | CES2 (0.50) | CES2CES1L3MBTL1KMT2AMAPT | |
| SCHEMBL9900481 | 0.86 | CES2 (0.48) | CES2CES1L3MBTL1KMT2AMAPT | |
| SCHEMBL9900480 | 0.86 | CES2 (0.48) | CES2CES1L3MBTL1KMT2AMAPT | |
| SCHEMBL9898928 | 0.86 | CES2 (0.38) | CES2CES1L3MBTL1KMT2AMAPT | |
| SCHEMBL9898927 | 0.86 | CES2 (0.38) | CES2CES1L3MBTL1KMT2AMAPT | |
| SCHEMBL2048184 | 0.84 | LMNA (0.35) | CES2CES1L3MBTL1MAPTLMNA | |
| SCHEMBL2048180 | 0.84 | LMNA (0.35) | CES2CES1L3MBTL1MAPTLMNA | |
| SCHEMBL9898858 | 0.81 | CES2 (0.43) | CES2CES1L3MBTL1KMT2AMAPT | |
| SCHEMBL9898856 | 0.81 | CES2 (0.43) | CES2CES1L3MBTL1KMT2AMAPT | |
| SCHEMBL211644 | 0.79 | LMNA (0.53) | CES2CES1L3MBTL1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8748531-B2 | Polymers functionalized with oxime compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2014-06-10 | — | — | US | claimed |
| US-20120149833-A1 | POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP | BRIDGESTONE CORPORATION (JP) | 2012-06-14 | — | — | US | claimed |
| CN-103282386-B | Polymers functionalized with oxime compounds containing acyl groups | BRIDGESTONE CORP | 2015-07-22 | — | — | CN | disclosed |
| EP-2649102-B1 | POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP | BRIDGESTONE CORP (JP) | 2014-11-26 | — | — | EP | disclosed |
| US-8748531-B2 | Polymers functionalized with oxime compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2014-06-10 | — | — | US | disclosed |
| US-20120149833-A1 | POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP | BRIDGESTONE CORPORATION (JP) | 2012-06-14 | — | — | US | disclosed |