Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | HPGD | P15428 | 8/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | KDM5A | P29375 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | FPR1 | P21462 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11650846 | 0.74 | HSD17B10 (0.41) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL3794931 | 0.74 | KDM4E (0.64) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL8149466 | 0.72 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL7117489 | 0.72 | HPGD (0.45) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL12566682 | 0.72 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL9256546 | 0.69 | MAPT (0.49) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL3678909 | 0.69 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL6060630 | 0.67 | HSD17B10 (0.47) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL4919077 | 0.67 | ATM (0.55) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL19734298 | 0.65 | KDM5A (0.45) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012078210-A1 | CRTH2 MODULATORS AND PREPARATION THEREOF | IRONWOOD PHARMACEUTICALS, INC. (US) | 2012-06-14 | — | — | WO | claimed |
| WO-2020113094-A1 | PYRROLE AND PYRAZOLE COMPOUNDS AND METHODS OF USE THEREOF | NUVATION BIO INC. (US) | 2020-06-04 | — | — | WO | disclosed |