Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.51 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | GNPAT | O15228 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 2/20 | 0.41 |
| ▸ | GLP1R | P43220 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002349 | 1.00 | MEN1 (0.55) | MEN1KMT2ANOD1C3AR1FOLH1 | |
| SCHEMBL14217259 | 0.95 | MEN1 (0.59) | MEN1KMT2ANOD1FOLH1EPHX2 | |
| SCHEMBL4186386 | 0.88 | C3AR1 (0.59) | MEN1KMT2ANOD1C3AR1FOLH1 | |
| SCHEMBL4186382 | 0.88 | C3AR1 (0.59) | MEN1KMT2ANOD1C3AR1FOLH1 | |
| SCHEMBL24602814 | 0.86 | NOD1 (0.63) | NOD1EPHX2GLP1R | |
| SCHEMBL2338931 | 0.85 | C3AR1 (0.47) | MEN1KMT2ANOD1C3AR1FOLH1 | |
| SCHEMBL2338925 | 0.85 | C3AR1 (0.47) | MEN1KMT2ANOD1C3AR1FOLH1 | |
| SCHEMBL15871316 | 0.85 | ALB (0.56) | MEN1KMT2ANOD1FOLH1GNPAT | |
| SCHEMBL24418072 | 0.83 | FOLH1 (0.48) | MEN1KMT2ANOD1FOLH1EPHX2 | |
| SCHEMBL6668178 | 0.83 | NOD1 (0.62) | NOD1GNPAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2648735-A2 | GRANZYME B INHIBITOR COMPOSITIONS, METHODS AND USES FOR PROMOTING WOUND HEALING | The University Of British Columbia (CA) | 2013-10-16 | — | — | EP | claimed |
| WO-2012076985-A2 | GRANZYME B INHIBITOR COMPOSITIONS, METHODS AND USES FOR PROMOTING WOUND HEALING | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2012-06-14 | — | — | WO | claimed |
| EP-2648735-A2 | GRANZYME B INHIBITOR COMPOSITIONS, METHODS AND USES FOR PROMOTING WOUND HEALING | The University Of British Columbia (CA) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012076985-A2 | GRANZYME B INHIBITOR COMPOSITIONS, METHODS AND USES FOR PROMOTING WOUND HEALING | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2012-06-14 | — | — | WO | disclosed |