Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 18/20 | 0.59 |
| ▸ | CHRM3 | P20309 | 18/20 | 0.59 |
| ▸ | CHRM5 | P08912 | 17/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28540751 | 0.74 | CHRM1 (0.74) | CHRM1CHRM3CHRM5CHRM2 | |
| SCHEMBL28909842 | 0.73 | CHRM1 (0.71) | CHRM1CHRM3CHRM5CHRM2 | |
| SCHEMBL11579712 | 0.72 | TRPM8 (0.44) | CHRM3CHRM2 | |
| SCHEMBL11500743 | 0.71 | TRPM8 (0.46) | — | |
| SCHEMBL16292695 | 0.71 | CHRM1 (0.54) | CHRM1CHRM3CHRM5CHRM2 | |
| SCHEMBL18763039 | 0.71 | TRPM8 (0.67) | CHRM3CHRM2 | |
| SCHEMBL9672698 | 0.70 | CHRM1 (0.51) | CHRM1CHRM3CHRM5CHRM2 | |
| SCHEMBL16292719 | 0.70 | CHRM1 (0.50) | CHRM1CHRM3CHRM5CHRM2 | |
| SCHEMBL4960958 | 0.69 | CHRM1 (0.49) | CHRM1CHRM3CHRM5CHRM2 | |
| SCHEMBL11442250 | 0.69 | TRPM8 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2384768-B1 | Phenylpropionamide compounds and the use thereof | PURDUE PHARMA LP (US) | 2013-08-21 | — | — | EP | disclosed |
| EP-2079485-B1 | PHENYLPROPIONAMIDE COMPOUNDS AND THE USE THEREOF | PURDUE PHARMA LP (US) | 2012-06-13 | — | — | EP | disclosed |