Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPY2R | P49146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11437818 | 0.78 | OPRM1 (0.45) | — | |
| SCHEMBL11437893 | 0.78 | OPRM1 (0.45) | — | |
| SCHEMBL11579712 | 0.70 | TRPM8 (0.44) | TRPM8MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11500743 | 0.69 | TRPM8 (0.46) | TRPM8MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL18763039 | 0.69 | TRPM8 (0.67) | TRPM8MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9905800 | 0.69 | CHRM1 (0.59) | — | |
| SCHEMBL11442252 | 0.67 | CHRM2 (0.36) | TRPM8MEN1KMT2ALMNA | |
| SCHEMBL17980354 | 0.65 | LMNA (0.39) | TRPM8PTGDR2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28162843 | 0.65 | AKT1 (0.48) | TRPM8MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL11808638 | 0.65 | AKT1 (0.43) | TRPM8KMT2AALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4217362-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-08-12 | — | — | US | disclosed |
| US-4212888-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
| US-4128663-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |