Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL990589 | 0.79 | — | — | |
| SCHEMBL28529710 | 0.77 | CYP2C19 (0.34) | SMPD1LMNAFDPSBLMTDP1 | |
| SCHEMBL29248119 | 0.76 | SMPD1 (0.31) | SMPD1LMNA | |
| SCHEMBL23633165 | 0.76 | SMPD1 (0.32) | SMPD1 | |
| SCHEMBL3892285 | 0.74 | SMPD1 (0.35) | SMPD1LMNAFDPSBLMTDP1 | |
| SCHEMBL27757592 | 0.72 | LAP3 (0.35) | SMPD1FDPSBLMTDP1 | |
| SCHEMBL466569 | 0.72 | LAP3 (0.35) | SMPD1LMNAFDPSBLMTDP1 | |
| SCHEMBL538990 | 0.71 | — | — | |
| SCHEMBL4940649 | 0.70 | — | — | |
| SCHEMBL11151287 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008939-B1 | INTUMESCENT COMPOSITION | GREAT LAKES CHEMICAL CORPORATION (US) | 1983-02-16 | — | — | EP | claimed |
| US-4345002-A | CYCLIC NITROGEN COMPOUND, HYDROXY CONTAINING ORGANO-PHOSPHORUS COMPOUND, AND A PHOSPHORUS CONTAINING ACID | GREAT LAKES CHEMICAL CORPORATION (US) | 1982-08-17 | — | — | US | claimed |
| US-4241145-A | TRIAMINO-TRIAZINE, COPOLYCONDENSED VINYLPHOSPHONATE, A PHOSPHORUS-CONTAINING ACID AND WATER FIREPROOF WOOD SUBSTRATES | VELSICOL CHEMICAL CORPORATION (US) | 1980-12-23 | — | — | US | claimed |
| EP-0008939-A2 | Intumescent composition | GREAT LAKES CHEMICAL CORPORATION (US) | 1980-03-19 | — | — | EP | claimed |
| EP-2448950-A1 | SYNTHESIS OF N4- (2, 2-DIMETHYL-4- [ (DIHYDROGEN PHOSPHONOXY]-3-OXO-5-PYRIDO [1, 4]OXAZIN-6-YL)-5-FLUORO-N2- (3, 4, 5,-TRIMETHOXYPHENYL) -2, 4- PYRIMIDINEDIAMINE DISODIUM SALT | Rigel Pharmaceuticals, Inc. (US) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011002999-A1 | SYNTHESIS OF N4- (2, 2-DIMETHYL-4- [ (DIHYDROGEN PHOSPHONOXY ] -3-OXO-5-PYRIDO [1, 4] OXAZIN-6-YL)-5-FLUORO-N2- (3, 4, 5,-TRIMETHOXYPHENYL) -2, 4- PYRIMIDINEDIAMINE DISODIUM SALT | RIGEL PHARMACEUTICALS, INC. (US) | 2011-01-06 | — | — | WO | disclosed |
| EP-0008939-B1 | INTUMESCENT COMPOSITION | GREAT LAKES CHEMICAL CORPORATION (US) | 1983-02-16 | — | — | EP | disclosed |
| US-4345002-A | CYCLIC NITROGEN COMPOUND, HYDROXY CONTAINING ORGANO-PHOSPHORUS COMPOUND, AND A PHOSPHORUS CONTAINING ACID | GREAT LAKES CHEMICAL CORPORATION (US) | 1982-08-17 | — | — | US | disclosed |
| EP-0008939-A2 | Intumescent composition | GREAT LAKES CHEMICAL CORPORATION (US) | 1980-03-19 | — | — | EP | disclosed |