Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31461600 | 0.87 | KMT2A (0.33) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL414149 | 0.82 | TP53 (0.35) | KMT2ATSHRLMNACHRM2CHRM4 | |
| SCHEMBL27842795 | 0.78 | — | — | |
| SCHEMBL28010889 | 0.78 | — | — | |
| SCHEMBL17078105 | 0.78 | — | — | |
| SCHEMBL351872 | 0.76 | — | — | |
| SCHEMBL17236094 | 0.76 | — | — | |
| SCHEMBL1396394 | 0.76 | TP53 (0.38) | KMT2ATSHRCYP2C9GAAELANE | |
| SCHEMBL1396484 | 0.76 | TP53 (0.38) | KMT2ATSHRCYP2C9GAAELANE | |
| Hydrochloric Acid SCHEMBL18343842 | 0.76 | LMNA (0.43) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8569435-B2 | Amino acid mimetic copolymers and medical devices coated with the copolymers | ABBOTT LABORATORIES (US) | 2013-10-29 | — | — | US | disclosed |
| US-8197880-B2 | Methods for manufacturing amino acid mimetic copolymers and use of same | ABBOTT LABORATORIES (US) | 2012-06-12 | — | — | US | disclosed |
| US-8071705-B2 | Amino acid mimetic copolymers and medical devices coated with the copolymers | ABBOTT LABORATORIES (US) | 2011-12-06 | — | — | US | disclosed |
| US-8048975-B2 | Amino acid mimetic copolymers and medical devices coated with the copolymers | ABBOTT LABORATORIES (US) | 2011-11-01 | — | — | US | disclosed |
| US-20110160391-A1 | AMINO ACID MIMETIC COPOLYMERS AND MEDICAL DEVICES COATED WITH THE COPOLYMERS | ABBOTT LABORATORIES (US) | 2011-06-30 | — | — | US | disclosed |
| US-20110160331-A1 | AMINO ACID MIMETIC COPOLYMERS AND MEDICAL DEVICES COATED WITH THE COPOLYMERS | ABBOTT LABORATORIES (US) | 2011-06-30 | — | — | US | disclosed |
| US-20110160417-A1 | AMINO ACID MIMETIC COPOLYMERS AND MEDICAL DEVICES COATED WITH THE COPOLYMERS | ABBOTT LABORATORIES (US) | 2011-06-30 | — | — | US | disclosed |
| US-7928177-B2 | Amino acid mimetic copolymers and medical devices coated with the copolymers | ABBOTT LABORATORIES (US) | 2011-04-19 | — | — | US | disclosed |
| US-20100183798-A1 | METHODS FOR MANUFACTURING AMINO ACID MIMETIC COPOLYMERS AND USE OF SAME | ABBOTT LABORATORIES | 2010-07-22 | — | — | US | disclosed |
| US-7622537-B2 | copolymerizing an amino acid mimetic monomer and hydrophobic acrylate monomers; amino acid mimetic monomers selected to mimic the side chain of the amino acids Asn or gln can be a (meth)acryloyl derivative of 2-hydroxyacetamide, 3-hydroxypropionamide, alaninamide, lactamide; biocompatible; coated stent | ABBOTT LABORATORIES (US) | 2009-11-24 | — | — | US | disclosed |
| US-20080124450-A1 | copolymerizing an amino acid mimetic monomer and hydrophobic acrylate monomers; amino acid mimetic monomers selected to mimic the side chain of the amino acids Asn or gln can be a (meth)acryloyl derivative of 2-hydroxyacetamide, 3-hydroxypropionamide, alaninamide, lactamide; biocompatible; coated stent | ABBOTT LABORATORIES (US) | 2008-05-29 | — | — | US | disclosed |
| US-20080125514-A1 | Biocompatible polymers that include an amino acid mimetic monomer and one or more hydrophobic acrylate monomers, the amino acid mimetic monomers being selected to mimic the side chain of the amino acids asparagine or glutamine; mechanical strength, drug permeability | ABBOTT LABORATORIES (US) | 2008-05-29 | — | — | US | disclosed |