Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | RECQL | P46063 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9281433 | 0.85 | ADRB3 (0.66) | ADRB3KDM4ERECQLTDP1MAPT | |
| SCHEMBL9281429 | 0.85 | ADRB3 (0.66) | ADRB3KDM4ERECQLTDP1MAPT | |
| SCHEMBL1577102 | 0.85 | ADRB3 (0.66) | ADRB3KDM4ERECQLTDP1MAPT | |
| SCHEMBL9908052 | 0.76 | TRPV1 (0.44) | ADRB3NPC1 | |
| SCHEMBL4816663 | 0.74 | CYP19A1 (0.48) | ADRB3ADRB1NPC1 | |
| SCHEMBL1285429 | 0.72 | ADRB3 (0.42) | ADRB3KDM4EMAPTLMNAKMT2A | |
| SCHEMBL1474627 | 0.72 | ADRB3 (0.42) | ADRB3KDM4EMAPTLMNAKMT2A | |
| SCHEMBL13685630 | 0.72 | ADRB3 (0.42) | ADRB3KDM4EMAPTLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL1473679 | 0.71 | ADRB3 (0.41) | ADRB3KDM4EMAPTLMNAKMT2A | |
| SCHEMBL2336547 | 0.71 | CCNT1 (0.49) | KDM4EMAPTKMT2ATSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198330-B2 | Therapeutic or prophylactic agent for diabetes, obesity, dyslipidemia or metabolic syndrome comprising benzylamine derivative or pharmaceutically acceptable acid addition salt thereof | TORAY INDUSTRIES, INC. (JP) | 2012-06-12 | — | — | US | disclosed |
| US-20110124733-A1 | THERAPEUTIC OR PROPHYLACTIC AGENT FOR DIABETES, OBESITY, DYSLIPIDEMIA OR METABOLIC SYNDROME COMPRISING BENZYLAMINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE ACID | TORAY INDUSTRIES, INC. (JP) | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124733-A1 | THERAPEUTIC OR PROPHYLACTIC AGENT FOR DIABETES, OBESITY, DYSLIPIDEMIA OR METABOLIC SYNDROME COMPRISING BENZYLAMINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE ACID | GPR119, LIPC, LIPA | ADRB3 64/4885KDM4E 3716/4885RECQL 1154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.