Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 4/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13678665 | 0.91 | ESR1 (0.52) | SLC5A2ESR1CA9CA12CA1 | |
| SCHEMBL1688099 | 0.85 | FOLH1 (0.51) | SLC5A2ESR1CA9CA12CA1 | |
| SCHEMBL9906325 | 0.84 | FOLH1 (0.54) | SLC5A2ESR1CA9CA12CA1 | |
| SCHEMBL9906321 | 0.83 | FOLH1 (0.55) | SLC5A2ESR1CA9CA12CA1 | |
| SCHEMBL10145843 | 0.83 | ESR1 (0.43) | SLC5A2ESR1CA9CA12CA1 | |
| SCHEMBL9906326 | 0.82 | FOLH1 (0.56) | SLC5A2ESR1CA9CA12CA1 | |
| SCHEMBL9906327 | 0.81 | FOLH1 (0.52) | SLC5A2ESR1CA9CA12CA1 | |
| SCHEMBL13780502 | 0.81 | FOLH1 (0.48) | SLC5A2ESR1CA9ALBFOLH1 | |
| SCHEMBL14619724 | 0.81 | USP2 (0.45) | SLC5A2ESR1CA9CA12CA1 | |
| SCHEMBL9906226 | 0.81 | ALB (0.49) | ESR1CA9ALBFOLH1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198031-B2 | Using epidermal growth factor receptor complexes to diagnose and prognose health in cancer patients; drug screening | MONOGRAM BIOSCIENCES, INC. (US) | 2012-06-12 | — | — | US | disclosed |
| US-20080233602-A1 | Detecting and profiling molecular complexes | MONOGRAM BIOSCIENCES, INC. | 2008-09-25 | — | — | US | disclosed |