SCHEMBL9906327

SCHEMBL9906327

O=C(CSCCC(=O)ON1C(=O)CCC1=O)NCCCOCCOCCOCCCNC(=O)c1ccc(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c(C(=O)O)c1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 2/20 0.52
▸ ALB P02768 2/20 0.49
▸ ESR1 P03372 1/20 0.46
▸ SLC5A2 P31639 2/20 0.45
▸ CA9 Q16790 4/20 0.44
▸ CA12 O43570 3/20 0.44
▸ CA1 P00915 3/20 0.44
▸ CA2 P00918 3/20 0.44
▸ USP2 O75604 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ FKBP1A P62942 1/20 0.43
▸ HAVCR2 Q8TDQ0 1/20 0.42
▸ AVPR2 P30518 1/20 0.42
▸ OXTR P30559 1/20 0.42
▸ AVPR1A P37288 1/20 0.42
▸ ADORA3 P0DMS8 1/20 0.42
▸ ADORA2A P29274 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9906326 0.96 FOLH1 (0.56) FOLH1ALBESR1SLC5A2CA9
SCHEMBL9906192 0.96 ALB (0.49) FOLH1ALBESR1SLC5A2CA9
SCHEMBL9906325 0.96 FOLH1 (0.54) FOLH1ALBESR1SLC5A2CA9
SCHEMBL9906321 0.95 FOLH1 (0.55) FOLH1ALBESR1SLC5A2CA9
SCHEMBL1688099 0.94 FOLH1 (0.51) FOLH1ALBESR1SLC5A2CA9
SCHEMBL9906229 0.92 FOLH1 (0.51) FOLH1ALBESR1USP2L3MBTL1
SCHEMBL9906261 0.91 ALB (0.52) FOLH1ALBSLC5A2
SCHEMBL9906226 0.90 ALB (0.49) FOLH1ALBESR1CA9USP2
SCHEMBL13678665 0.89 ESR1 (0.52) FOLH1ALBESR1SLC5A2CA9
SCHEMBL13678640 0.89 ALB (0.53) FOLH1ALBESR1SLC5A2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1673399-B1 DETECTING AND PROFILING MOLECULAR COMPLEXES MONOGRAM BIOSCIENCES INC (US) 2017-04-05 — — EP disclosed
US-8198031-B2 Using epidermal growth factor receptor complexes to diagnose and prognose health in cancer patients; drug screening MONOGRAM BIOSCIENCES, INC. (US) 2012-06-12 — — US disclosed
US-20090011432-A1 Detecting and Profiling Molecular Complexes MONOGRAM BIOSCIENCES, INC. (US) 2009-01-08 — — US disclosed
US-20080233602-A1 Detecting and profiling molecular complexes MONOGRAM BIOSCIENCES, INC. 2008-09-25 — — US disclosed
US-7402397-B2 Detecting and profiling molecular complexes MONOGRAM BIOSCIENCES, INC. (US) 2008-07-22 — — US disclosed
US-7255999-B2 Detection of preferential polypetide in sample; otain sample containing preferential polyeptide, electrophorese, incubate with probe, detect signal from probe and recover polypeptide MONOGRAM BIOSCIENCES, INC. (US) 2007-08-14 — — US disclosed
US-7160735-B2 Tagged microparticle compositions and methods MONOGRAM BIOSCIENCES, INC. (US) 2007-01-09 — — US disclosed
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