Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22917361 | 0.93 | CXCR4 (0.56) | CXCR4MEN1KMT2ACHRM2RAB9A | |
| SCHEMBL20625943 | 0.85 | CXCR4 (0.53) | CXCR4MEN1KMT2ACHRM2RAB9A | |
| SCHEMBL18088394 | 0.84 | RAB9A (0.60) | CXCR4MEN1KMT2ACHRM2RAB9A | |
| SCHEMBL13540715 | 0.83 | KMT2A (0.58) | CXCR4MEN1KMT2ACHRM2RAB9A | |
| SCHEMBL13792281 | 0.80 | RAB9A (0.56) | CXCR4MEN1KMT2ACHRM2RAB9A | |
| SCHEMBL9906705 | 0.79 | CXCR4 (0.44) | CXCR4MEN1KMT2ACHRM2RAB9A | |
| SCHEMBL9906706 | 0.79 | CXCR4 (0.44) | CXCR4MEN1KMT2ACHRM2RAB9A | |
| SCHEMBL14845923 | 0.77 | CXCR4 (0.46) | CXCR4MEN1KMT2ACHRM2RAB9A | |
| SCHEMBL9906709 | 0.76 | CXCR4 (0.55) | CXCR4MEN1KMT2AHDAC6HDAC3 | |
| SCHEMBL9906713 | 0.75 | CXCR4 (0.46) | CXCR4EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198303-B2 | Methods of use and compositions for the diagnosis and treatment of infectious diseases | SEQUELLA, INC. (US) | 2012-06-12 | — | — | US | disclosed |