Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13540713 | 0.86 | KMT2A (0.52) | CXCR4MEN1KMT2ACHRM2ALDH1A1 | |
| SCHEMBL22917361 | 0.82 | CXCR4 (0.56) | CXCR4MEN1KMT2ACHRM2HDAC6 | |
| SCHEMBL9906707 | 0.79 | CXCR4 (0.51) | CXCR4MEN1KMT2ACHRM2HDAC6 | |
| SCHEMBL1625040 | 0.77 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1TSHRRAD52 | |
| SCHEMBL20625943 | 0.75 | CXCR4 (0.53) | CXCR4MEN1KMT2ACHRM2HDAC6 | |
| SCHEMBL9906708 | 0.75 | SMN1; SMN2 (0.42) | CXCR4ALDH1A1TSHREPHX2 | |
| SCHEMBL18088394 | 0.75 | RAB9A (0.60) | CXCR4MEN1KMT2ACHRM2HDAC6 | |
| SCHEMBL9906706 | 0.73 | CXCR4 (0.44) | CXCR4MEN1KMT2ACHRM2HDAC6 | |
| SCHEMBL1967608 | 0.73 | NPC1 (0.46) | CXCR4MEN1KMT2ACHRM2ALDH1A1 | |
| SCHEMBL13792281 | 0.71 | RAB9A (0.56) | CXCR4MEN1KMT2ACHRM2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198303-B2 | Methods of use and compositions for the diagnosis and treatment of infectious diseases | SEQUELLA, INC. (US) | 2012-06-12 | — | — | US | disclosed |