Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.52 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.50 |
| ▸ | INPP5B | P32019 | 1/20 | 0.50 |
| ▸ | INPP5A | Q14642 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.49 |
| ▸ | TUBB | P07437 | 3/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxi-4503 SCHEMBL29370292 | 0.84 | CYP1A1 (0.54) | SRCCYP1A1CYP1A2CYP1B1TUBB4A | |
| Oxi-4503 SCHEMBL12677563 | 0.84 | CYP1A1 (0.54) | SRCCYP1A1CYP1A2CYP1B1TUBB4A | |
| SCHEMBL14175308 | 0.84 | CYP1A1 (0.57) | SRCCYP1A1CYP1A2CYP1B1TUBB4A | |
| SCHEMBL14175295 | 0.84 | CYP1A1 (0.57) | SRCCYP1A1CYP1A2CYP1B1TUBB4A | |
| SCHEMBL17145746 | 0.84 | SRC (0.50) | SRCCYP1A1CYP1A2CYP1B1INPPL1 | |
| SCHEMBL14175306 | 0.83 | CYP1A1 (0.56) | CYP1A1CYP1A2CYP1B1TUBB4ATUBB | |
| Oxi-4503 SCHEMBL30934510 | 0.83 | CYP1A1 (0.52) | SRCCYP1A1CYP1A2CYP1B1TUBB4A | |
| SCHEMBL14175305 | 0.82 | TUBB1 (0.51) | CYP1A1CYP1A2CYP1B1TUBB4ATUBB | |
| SCHEMBL14175299 | 0.81 | TUBB1 (0.50) | CYP1A1CYP1A2CYP1B1TUBB4ATUBB | |
| SCHEMBL14175309 | 0.80 | CYP1A1 (0.48) | CYP1A1CYP1A2CYP1B1INPPL1INPP5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198302-B2 | Anticancer agent having a quinone, quinone prodrug, catechol or catechol prodrug moiety; free of combretastatin A-1 | OXIGENE, INC. (US) | 2012-06-12 | — | — | US | disclosed |
| US-7384925-B2 | 2' Hydroxy-3'-bromo-3,4,4',5-tetramethoxy-(Z)-stilbene; antimitotic agent; inhibits the assembly of tubulin into microtubules; anticarcinogenic: solid tumor cancers, neovascularization; tubulin-binding stilbenoid analogs structurally related to combretastatin A-1 and A-4 (extract from willow tree) | OXIGENE, INC. (US) | 2008-06-10 | — | — | US | disclosed |