SCHEMBL990711

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL68869	0.91	MAPK1 (0.63)	MAPK1KDM4EL3MBTL1LCKGABRP
	SCHEMBL13067536	0.83	MAPK1 (0.52)	MAPK1KDM4EL3MBTL1LCKGABRP
	SCHEMBL13165465	0.83	KCNJ1 (0.52)	MAPK1KDM4EL3MBTL1KCNJ1ALDH1A1
	SCHEMBL5700876	0.83	KDM4E (0.61)	MAPK1KDM4EL3MBTL1LCKGABRP
	SCHEMBL1858691	0.81	POLB (0.59)	MAPK1L3MBTL1ALDH1A1LMNACYP1A2
	SCHEMBL428719	0.81	MAPK1 (0.53)	MAPK1KDM4EL3MBTL1LCKGABRP
	SCHEMBL13524601	0.79	SIRT6 (0.67)	MAPK1KDM4EL3MBTL1LCKGABRP
	SCHEMBL2134366	0.79	MAPK1 (0.52)	MAPK1KDM4EL3MBTL1LCKGABRP
	SCHEMBL7995074	0.79	MAPK1 (0.52)	MAPK1KDM4EL3MBTL1LCKGABRP
	SCHEMBL22119742	0.79	MAPK1 (0.52)	MAPK1KDM4EL3MBTL1LCKGABRP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.