Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRYAB | P02511 | 5/20 | 0.74 |
| ▸ | USP2 | O75604 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | CRYAA | P02489 | 1/20 | 0.73 |
| ▸ | PTGES | O14684 | 2/20 | 0.61 |
| ▸ | FNTA | P49354 | 2/20 | 0.55 |
| ▸ | FNTB | P49356 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL990785 | 1.00 | CRYAB (0.74) | CRYABUSP2ALDH1A1CYP3A4MAPT | |
| SCHEMBL19199340 | 0.90 | CRYAB (0.77) | CRYABUSP2ALDH1A1CYP3A4MAPT | |
| SCHEMBL19194028 | 0.88 | CRYAB (0.74) | CRYABUSP2ALDH1A1CYP3A4MAPT | |
| SCHEMBL19194027 | 0.88 | CRYAB (0.74) | CRYABUSP2ALDH1A1CYP3A4MAPT | |
| SCHEMBL288307 | 0.87 | CRYAB (0.80) | CRYABUSP2ALDH1A1CYP3A4MAPT | |
| SCHEMBL13499192 | 0.87 | CRYAB (0.80) | CRYABUSP2ALDH1A1CYP3A4MAPT | |
| SCHEMBL6130528 | 0.87 | CRYAB (0.80) | CRYABUSP2ALDH1A1CYP3A4MAPT | |
| SCHEMBL568417 | 0.87 | CRYAB (0.80) | CRYABUSP2ALDH1A1CYP3A4MAPT | |
| SCHEMBL26237645 | 0.87 | CRYAB (0.80) | CRYABUSP2ALDH1A1CYP3A4MAPT | |
| SCHEMBL288306 | 0.87 | CRYAB (0.80) | CRYABUSP2ALDH1A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120195988-A1 | Therapeutic Uses for Plants of the Capsicum Genus | REZAI-FARD ALI (GB) | 2012-08-02 | — | — | US | disclosed |
| EP-2456453-A1 | THERAPEUTIC USES FOR PLANTS OF THE CAPSICUM GENUS | Rezai-Fard, Ali (GB) | 2012-05-30 | — | — | EP | disclosed |
| WO-2011010090-A1 | THERAPEUTIC USES FOR PLANTS OF THE CAPSICUM GENUS | REZAI-FARD ALI (GB) | 2011-01-27 | — | — | WO | disclosed |