Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13103029 | 0.91 | KDM4E (0.30) | KDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL13103021 | 0.88 | MTNR1A (0.31) | — | |
| SCHEMBL13103075 | 0.88 | ALDH1A1 (0.36) | KDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL9908157 | 0.87 | PSMB8 (0.38) | — | |
| SCHEMBL9908167 | 0.86 | PRSS1 (0.31) | — | |
| SCHEMBL9908189 | 0.85 | — | — | |
| SCHEMBL9908197 | 0.83 | PTGER1 (0.31) | KDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL9908160 | 0.83 | — | — | |
| SCHEMBL9908166 | 0.81 | — | — | |
| SCHEMBL9908171 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8197759-B2 | Bodipy fluorophore dyes useful in the labeling and identification of proteins; highly soluble | MONTANA STATE UNIVERSITY (US) | 2012-06-12 | — | — | US | disclosed |
| US-8197758-B2 | Bodipy fluorophore dyes useful in the labeling and identification of proteins; highly soluble | MONTANA STATE UNIVERSITY (US) | 2012-06-12 | — | — | US | disclosed |
| US-7833799-B2 | Zwitterionic dyes for labeling in proteomic and other biological analyses | MONTANA STATE UNIVERSITY (US) | 2010-11-16 | — | — | US | disclosed |
| US-20100252433-A1 | NOVEL OPTICAL LABELING MOLECULES FOR PROTEOMICS AND OTHER BIOLOGICAL ANALYSES | NATIONAL SCIENCE FOUNDATION | 2010-10-07 | — | — | US | disclosed |
| US-20100203645-A1 | NOVEL ZWITTERIONIC DYES FOR LABELING IN PROTEOMIC AND OTHER BIOLOGICAL ANAYLSES | NATIONAL SCIENCE FOUNDATION | 2010-08-12 | — | — | US | disclosed |
| US-20100036133-A1 | NOVEL ZWITTERIONIC DYES FOR LABELING IN PROTEOMIC AND OTHER BIOLOGICAL ANALYSES | MONTANA STATE UNIVERSITY (US) | 2010-02-11 | — | — | US | disclosed |
| US-7582260-B2 | Zwitterionic dyes for labeling in proteomic and other biological analyses | MONTANA STATE UNIVERSITY (US) | 2009-09-01 | — | — | US | disclosed |
| US-20070259333-A1 | NOVEL ZWITTERIONIC DYES FOR LABELING IN PROTEOMIC AND OTHER BIOLOGICAL ANALYSES | MONTANA STATE UNIVERSITY (US) | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100252433-A1 | NOVEL OPTICAL LABELING MOLECULES FOR PROTEOMICS AND OTHER BIOLOGICAL ANALYSES | PTMS, CHAMP1, RAB5IF | KDM4E 2452/4885ALDH1A1 2137/4885ALOX15 2008/4885 |
| US-20100203645-A1 | NOVEL ZWITTERIONIC DYES FOR LABELING IN PROTEOMIC AND OTHER BIOLOGICAL ANAYLSES | ACP1, ANXA5, CHAMP1 | KDM4E 1314/4885ALDH1A1 2412/4885ALOX15 3850/4885 |
| US-20100036133-A1 | NOVEL ZWITTERIONIC DYES FOR LABELING IN PROTEOMIC AND OTHER BIOLOGICAL ANALYSES | CHAMP1, ANXA5, ANXA3 | KDM4E 1701/4885ALDH1A1 3530/4885ALOX15 4382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.