Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.33 |
| ▸ | USP21 | Q9UK80 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27952604 | 0.98 | NPSR1 (0.42) | NPSR1DGAT1MAPTCYP4F2CYP4A11 | |
| SCHEMBL9908329 | 0.98 | NPSR1 (0.45) | NPSR1DGAT1MAPTCYP4F2CYP4A11 | |
| SCHEMBL1012254 | 0.94 | DGAT1 (0.42) | NPSR1DGAT1MAPTCYP4F2CYP4A11 | |
| SCHEMBL978083 | 0.89 | DGAT1 (0.50) | NPSR1DGAT1MAPTCYP4F2CYP4A11 | |
| SCHEMBL762180 | 0.81 | NPSR1 (0.45) | NPSR1MAPTCYP4F2CYP4A11CYP3A4 | |
| SCHEMBL14557008 | 0.80 | DGAT1 (0.34) | DGAT1CYP4F2CYP4A11RIPK1TSHR | |
| SCHEMBL11377177 | 0.79 | NPSR1 (0.44) | NPSR1MAPTCYP4F2CYP4A11CYP3A4 | |
| Hydrochloric Acid SCHEMBL23727124 | 0.79 | DGAT1 (0.37) | NPSR1DGAT1KMT2A | |
| SCHEMBL13480695 | 0.79 | DGAT1 (0.37) | NPSR1DGAT1MAPT | |
| SCHEMBL15925090 | 0.78 | NPSR1 (0.47) | NPSR1MAPTCYP4F2CYP4A11CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689664-B | Tricyclic heteroaryl substituted quinoline and azaquinoline compounds as PAR4 inhibitors | 百时美施贵宝公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-112805267-A | Carboxamide and sulfonamide derivatives as TEAD modulators | 豪夫迈·罗氏有限公司 | 2021-05-14 | — | — | CN | disclosed |
| US-8198016-B2 | Patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-06-12 | — | — | US | disclosed |
| US-20090286188-A1 | Patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2009-11-19 | — | — | US | disclosed |