SCHEMBL9908459

SCHEMBL9908459

Cn1cc(C(=O)Nc2ccccc2C2CC2C2CCCC2)c(C(F)F)n1

nearest known ligand 0.45

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 20/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL192918 0.96 IRAK4 (0.44) IRAK4
SCHEMBL3800558 0.96 IRAK4 (0.44) IRAK4
SCHEMBL10017884 0.96 IRAK4 (0.44) IRAK4
SCHEMBL13186326 0.96 IRAK4 (0.44) IRAK4
SCHEMBL12482269 0.96 IRAK4 (0.44) IRAK4
SCHEMBL9908457 0.96 IRAK4 (0.44) IRAK4
SCHEMBL1938177 0.96 IRAK4 (0.44) IRAK4
SCHEMBL2592337 0.96 IRAK4 (0.44) IRAK4
SCHEMBL411744 0.96 IRAK4 (0.44) IRAK4
SCHEMBL68347 0.96 IRAK4 (0.44) IRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8198215-B2 Methods for protecting seeds Sygenta Crop Protection LLC (US) 2012-06-12 US disclosed
US-8198215-B2 Methods for protecting seeds Sygenta Crop Protection LLC (US) 2012-06-12 US disclosed
US-20090054233-A1 METHODS FOR PROTECTING USEFUL PLANTS OR PLANT PROPAGATION MATERIAL SYNGENTA CROP PROTECTION, INC. 2009-02-26 US disclosed
US-20090054233-A1 METHODS FOR PROTECTING USEFUL PLANTS OR PLANT PROPAGATION MATERIAL SYNGENTA CROP PROTECTION, INC. 2009-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054233-A1 METHODS FOR PROTECTING USEFUL PLANTS OR PLANT PROPAGATION MATERIAL POT1, PNMT, TUBB3 IRAK4 4776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.