Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A11 | P48066 | 7/20 | 0.42 |
| ▸ | SLC6A1 | P30531 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26302681 | 0.99 | SLC6A11 (0.42) | SLC6A11SLC6A1MEN1KMT2AMAPT | |
| SCHEMBL9908638 | 0.99 | SLC6A11 (0.42) | SLC6A11SLC6A1MEN1KMT2AMAPT | |
| SCHEMBL14978147 | 0.99 | SLC6A11 (0.42) | SLC6A11SLC6A1MEN1KMT2AMAPT | |
| SCHEMBL26302685 | 0.99 | SLC6A11 (0.42) | SLC6A11SLC6A1MEN1KMT2AMAPT | |
| SCHEMBL26302691 | 0.99 | SLC6A11 (0.42) | SLC6A11SLC6A1MEN1KMT2AMAPT | |
| SCHEMBL26302692 | 0.94 | CNR1 (0.42) | SLC6A11SLC6A1MEN1KMT2AMAPT | |
| SCHEMBL24383294 | 0.93 | SLC6A11 (0.42) | SLC6A11SLC6A1MEN1KMT2ATP53 | |
| SCHEMBL9604514 | 0.93 | SLC6A11 (0.42) | SLC6A11SLC6A1MEN1KMT2ATP53 | |
| SCHEMBL16843276 | 0.93 | SLC6A11 (0.42) | SLC6A11SLC6A1MEN1KMT2ATP53 | |
| SCHEMBL17231722 | 0.93 | SLC6A11 (0.42) | SLC6A11SLC6A1MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170107511-A1 | OLIGONUCLEOTIDE END CAPS | BANK OF AMERICA, N.A. | 2017-04-20 | — | — | US | disclosed |
| US-9512164-B2 | Oligonucleotide end caps | ALNYLAM PHARMACEUTICALS, INC. (US) | 2016-12-06 | — | — | US | disclosed |
| US-9512164-B2 | Oligonucleotide end caps | ALNYLAM PHARMACEUTICALS, INC. (US) | 2016-12-06 | — | — | US | disclosed |
| US-20120142101-A1 | OLIGONUCLEOTIDE END CAPS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-06-07 | — | — | US | disclosed |