Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.37 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL768052 | 1.00 | BCHE (0.37) | BCHERNASE1POLBABCB1 | |
| SCHEMBL18269557 | 0.85 | BCHE (0.40) | BCHERNASE1ABCB1 | |
| SCHEMBL768248 | 0.84 | — | — | |
| SCHEMBL9908696 | 0.84 | — | — | |
| SCHEMBL9908698 | 0.82 | LGALS9 (0.40) | BCHERNASE1 | |
| SCHEMBL767835 | 0.82 | LGALS9 (0.40) | BCHERNASE1 | |
| SCHEMBL16943159 | 0.80 | — | — | |
| SCHEMBL768252 | 0.80 | — | — | |
| SCHEMBL767953 | 0.80 | — | — | |
| SCHEMBL768015 | 0.79 | RNASE1 (0.42) | BCHERNASE1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9512164-B2 | Oligonucleotide end caps | ALNYLAM PHARMACEUTICALS, INC. (US) | 2016-12-06 | — | — | US | disclosed |
| US-20120142101-A1 | OLIGONUCLEOTIDE END CAPS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-06-07 | — | — | US | disclosed |