Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 20/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL992650 | 0.90 | NPC1 (0.45) | GRM5 | |
| SCHEMBL990862 | 0.90 | NPC1 (0.45) | GRM5 | |
| SCHEMBL989508 | 0.89 | GRM5 (0.46) | GRM5 | |
| SCHEMBL991609 | 0.84 | GRM5 (0.46) | GRM5 | |
| SCHEMBL990100 | 0.82 | GRM5 (0.47) | GRM5 | |
| SCHEMBL990750 | 0.82 | GRM5 (0.56) | GRM5 | |
| SCHEMBL989481 | 0.79 | GRM5 (0.47) | GRM5 | |
| SCHEMBL990155 | 0.79 | GRM5 (0.47) | GRM5 | |
| SCHEMBL990050 | 0.79 | ALDH1A1 (0.48) | GRM5 | |
| SCHEMBL991105 | 0.79 | ALDH1A1 (0.48) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2320892-A2 | COMBINATION PRODUCTS | Novartis AG (CH) | 2011-05-18 | — | — | EP | disclosed |
| EP-2272509-A1 | New Uses of metabotropic glutamate receptors | Novartis AG (CH) | 2011-01-12 | — | — | EP | disclosed |