SCHEMBL9909116

SCHEMBL9909116

CC(C)=NNC(=O)CCCCC(=O)NN

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CTSD P07339 1/20 0.45
ALDH1A1 P00352 5/20 0.44
KDM4E B2RXH2 5/20 0.42
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
MAPT P10636 1/20 0.42
GAA P10253 2/20 0.42
THRB P10828 1/20 0.40
KDM5C P41229 1/20 0.40
PHF8 Q9UPP1 1/20 0.40
KDM2A Q9Y2K7 1/20 0.40
POLB P06746 1/20 0.40
LMNA P02545 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
HTT P42858 1/20 0.38
HPGD P15428 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9909115 0.89 KDM4E (0.49) ALDH1A1KDM4EKMT2AMEN1MAPT
SCHEMBL18222991 0.87 ALDH1A1 (0.51) ALDH1A1KDM4EKMT2AMEN1MAPT
SCHEMBL18222979 0.87 ALDH1A1 (0.51) ALDH1A1KDM4EKMT2AMEN1MAPT
SCHEMBL18275012 0.87 ALDH1A1 (0.51) ALDH1A1KDM4EKMT2AMEN1MAPT
SCHEMBL18275026 0.87 ALDH1A1 (0.51) ALDH1A1KDM4EKMT2AMEN1MAPT
SCHEMBL28525809 0.87 ALDH1A1 (0.51) ALDH1A1KDM4EKMT2AMEN1MAPT
SCHEMBL20323409 0.86 ALDH1A1 (0.44) ALDH1A1KDM4EKMT2AMEN1MAPT
SCHEMBL6836142 0.81 CTSD (0.50) CTSDALDH1A1KDM4EMAPTGAA
SCHEMBL6836233 0.81 CTSD (0.50) CTSDALDH1A1KDM4EMAPTGAA
Acetone SCHEMBL22554792 0.80 CTSD (0.59) CTSDALDH1A1KDM4EKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018112555-A1 AQUEOUS POLYMER COMPOSITION COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2018-06-28 WO disclosed
US-9790374-B2 Aqueous cross-linking compositions and methods COLUMBIA INSURANCE COMPANY (US) 2017-10-17 US disclosed
US-9040617-B2 Aqueous cross-linking compositions and methods COLUMBIA INSURANCE COMPANY, INC. (US) 2015-05-26 US disclosed
US-20120142847-A1 AQUEOUS CROSS-LINKING COMPOSITIONS AND METHODS COLUMBIA INSURANCE COMPANY (US) 2012-06-07 US disclosed