Sugi Predict

Sugi Predict / Compounds / SCHEMBL9909404

SCHEMBL9909404

SCHEMBL9909404

Cc1ccc2c(c1)OCCOCCOCCOCCOCCO2

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.59
▸ LMNA P02545 5/20 0.59
▸ HTT P42858 2/20 0.59
▸ BLM P54132 1/20 0.59
▸ KDM4E B2RXH2 3/20 0.57
▸ GAA P10253 2/20 0.57
▸ CRHBP P24387 2/20 0.54
▸ CRHR2 Q13324 2/20 0.54
▸ SMN1; SMN2 Q16637 2/20 0.54
▸ KMT2A Q03164 2/20 0.51
▸ NPC1 O15118 4/20 0.49
▸ RAB9A P51151 3/20 0.49
▸ CTNNB1 P35222 1/20 0.49
▸ WNT3A P56704 1/20 0.49
▸ ALDH1A1 P00352 1/20 0.48
▸ HSD17B10 Q99714 1/20 0.48
▸ MEN1 O00255 1/20 0.46
▸ PKM P14618 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30062655 1.00 MAPT (0.59) MAPTLMNAHTTBLMKDM4E
SCHEMBL15982275 1.00 MAPT (0.59) MAPTLMNAHTTBLMKDM4E
SCHEMBL15982303 1.00 MAPT (0.59) MAPTLMNAHTTBLMKDM4E
SCHEMBL11933408 1.00 MAPT (0.59) MAPTLMNAHTTBLMKDM4E
SCHEMBL13840327 1.00 MAPT (0.59) MAPTLMNAHTTBLMKDM4E
SCHEMBL16253986 1.00 MAPT (0.59) MAPTLMNAHTTBLMKDM4E
SCHEMBL15033875 0.94 LMNA (0.65) MAPTLMNAHTTBLMKDM4E
SCHEMBL11905 0.93 MAPT (0.53) MAPTLMNAHTTBLMKDM4E
SCHEMBL14410337 0.92 LMNA (0.52) MAPTLMNAHTTBLMKDM4E
SCHEMBL14176972 0.86 MAPT (0.46) MAPTLMNAHTTBLMKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220393174-A1 CROWN ETHERS AS ADDITIVES FOR SILICON-BASED LI-ION BATTERIES ENEVATE CORPORATION 2022-12-08 — — US disclosed
US-20220193249-A1 Conjugates And Conjugating Reagents Comprising A Linker That Includes At Least Two (-CH2-CH2-O-) Units In A Ring POLYTHERICS LIMITED (GB) 2022-06-23 — — US disclosed
US-20210226251-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH ELECTROLYTE CONTAINING CROWN ETHER BASED COMPOUNDS ENEVATE CORPORATION 2021-07-22 — — US disclosed
US-10654873-B2 Cytotoxic agents and conjugates thereof POLYTHERICS LIMITED (GB) 2020-05-19 — — US disclosed
US-20190328893-A1 Conjugates And Conjugating Reagents Comprising A Linker That Includes At Least Two (-CH2-CH2-0-) Units In A Ring POLYTHERICS LIMITED (GB) 2019-10-31 — — US disclosed
US-20190202839-A1 Novel Cytotoxic Agents And Conjugates Thereof ABZENA (CAMBRIDGE) LIMITED (GB) 2019-07-04 — — US disclosed
US-9786941-B2 Metal ionophores in PEM membranes GM Global Technology Operations LLC (US) 2017-10-10 — — US disclosed
US-9077038-B2 Lithium ion batteries GM Global Technology Operations LLC (US) 2015-07-07 — — US disclosed
US-9077038-B2 Lithium ion batteries GM Global Technology Operations LLC (US) 2015-07-07 — — US disclosed
US-20150105239-A1 CROWN ETHER CONTAINING PEM ELECTRODE GM GLOBAL TECH OPERATIONS INC (US) 2015-04-16 — — US disclosed
US-20120142937-A1 METHOD FOR COUPLING HALOGEN-SUBSTITUTED AROMATIC COMPOUNDS WITH ORGANIC COMPOUNDS COMPRISING TRIALKYLSILYL-SUBSTITUTED HETEROATOMS ZYLUM BETEILIGUNGSGESELLSCHAFT MBH & CO. PATENTE II KG (DE) 2012-06-07 — — US disclosed
WO-2010106078-A1 METHOD FOR COUPLING HALOGEN-SUBSTITUTED AROMATIC COMPOUNDS WITH ORGANIC COMPOUNDS COMPRISING TRIALKYLSILYL-SUBSTITUTED HETEROATOMS ZYLUM BETEILIGUNGSGESELLSCHAFT MBH & CO. PATENTE II KG (DE) 2010-09-23 — — WO disclosed
US-7795251-B2 3,4-dihydro-benzo[e][1,3]oxazin-2-ones NOVARTIS AG (CH) 2010-09-14 — — US disclosed
US-7795251-B2 3,4-dihydro-benzo[e][1,3]oxazin-2-ones NOVARTIS AG (CH) 2010-09-14 — — US disclosed
EP-0882717-B1 NITROGENOUS HETEROCYCLIC COMPOUNDS KYOWA HAKKO KIRIN CO LTD (JP) 2010-09-08 — — EP disclosed
EP-1805170-B1 MIF-INHIBITORS NOVARTIS AG (CH) 2010-04-14 — — EP disclosed
US-20090156588-A1 3,4-DIHYDRO-BENZO[E][1,3]OXAZIN-2-ONES NOVARTIS AG (CH) 2009-06-18 — — US disclosed
US-20090156588-A1 3,4-DIHYDRO-BENZO[E][1,3]OXAZIN-2-ONES NOVARTIS AG (CH) 2009-06-18 — — US disclosed
US-7378416-B2 MIF-inhibitors NOVARTIS AG (CH) 2008-05-27 — — US disclosed
US-7378416-B2 MIF-inhibitors NOVARTIS AG (CH) 2008-05-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10654873-B2 Cytotoxic agents and conjugates thereof CD2BP2, DDB1, DCLRE1A MAPT 4353/4885LMNA 3151/4885HTT 4547/4885
US-20120142937-A1 METHOD FOR COUPLING HALOGEN-SUBSTITUTED AROMATIC COMPOUNDS WITH ORGANIC COMPOUNDS COMPRISING TRIALKYLSILYL-SUBSTITUTED HETEROATOMS TYR, ALK, TTL MAPT 1726/4885LMNA 3396/4885HTT 198/4885
US-20090156588-A1 3,4-DIHYDRO-BENZO[E][1,3]OXAZIN-2-ONES CYP2C8, CYP2C18, CYP4B1 MAPT 2644/4885LMNA 2396/4885HTT 1050/4885
US-20190202839-A1 Novel Cytotoxic Agents And Conjugates Thereof CD2BP2, DDB1, DCLRE1A MAPT 4584/4885LMNA 3092/4885HTT 4711/4885
US-20190328893-A1 Conjugates And Conjugating Reagents Comprising A Linker That Includes At Least Two (-CH2-CH2-0-) Units In A Ring BCR, CD2BP2, LANCL1 MAPT 843/4885LMNA 3160/4885HTT 794/4885
US-20220193249-A1 Conjugates And Conjugating Reagents Comprising A Linker That Includes At Least Two (-CH2-CH2-O-) Units In A Ring BCR, CD2BP2, LANCL1 MAPT 941/4885LMNA 3400/4885HTT 814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.