SCHEMBL9909809

SCHEMBL9909809

CCCCCCOc1cc(C)c(OC)cc1/C=C/c1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.40
NFE2L2 Q16236 1/20 0.40
AHR P35869 1/20 0.38
PTGS2 P35354 2/20 0.38
ALOX5 P09917 1/20 0.38
PTGS1 P23219 1/20 0.38
MAOB P27338 5/20 0.37
MAOA P21397 4/20 0.37
CYP1A1 P04798 3/20 0.37
CYP1A2 P05177 3/20 0.37
CYP1B1 Q16678 3/20 0.37
CYP19A1 P11511 1/20 0.37
CNR2 P34972 1/20 0.37
ACHE P22303 2/20 0.36
TUBB4A P04350 1/20 0.36
TUBB P07437 1/20 0.36
TUBA3C P0DPH7 1/20 0.36
TUBA1B P68363 1/20 0.36
TUBA4A P68366 1/20 0.36
TUBB4B P68371 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9909806 0.89 AHR (0.49) AHRMAOBMAOACYP1A1CYP1A2
SCHEMBL13805762 0.86 NFE2L2 (0.40) TRPA1NFE2L2AHRPTGS2MAOB
SCHEMBL9909803 0.85 AHR (0.45) AHRMAOBMAOACYP1A1CYP1A2
SCHEMBL18159312 0.84 ALDH1A1 (0.35) AHRMAOBMAOA
SCHEMBL862607 0.83 AHR (0.42) AHRPTGS2PTGS1MAOBMAOA
SCHEMBL862619 0.83 SMPD1 (0.41) ALOX5
SCHEMBL12780790 0.83 ALDH1A1 (0.40) NFE2L2AHRPTGS2MAOBMAOA
SCHEMBL13805760 0.83 PDE4A (0.41) TRPA1NFE2L2CYP1A1CYP1A2CYP1B1
SCHEMBL13309559 0.82 CHRNA7 (0.48) TRPA1NFE2L2AHRCYP1A1CYP1A2
SCHEMBL13230035 0.82 CYP1A1 (0.38) NFE2L2AHRPTGS2MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192917-B2 Material for multiphoton fluorescence microscope and multiphoton fluorescence microscope RICOH COMPANY, LTD. (JP) 2012-06-05 US disclosed