⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23961875 | 0.80 | — | — | |
| SCHEMBL10522948 | 0.76 | — | — | |
| SCHEMBL9512525 | 0.73 | GABRP (0.31) | — | |
| SCHEMBL9510911 | 0.71 | GABRP (0.38) | — | |
| SCHEMBL9511236 | 0.69 | ALDH1A1 (0.31) | — | |
| SCHEMBL17999826 | 0.67 | — | — | |
| Methylsulfanylmethane SCHEMBL10656634 | 0.66 | — | — | |
| SCHEMBL5615220 | 0.65 | EPHX1 (0.42) | — | |
| SCHEMBL5270433 | 0.65 | — | — | |
| SCHEMBL18531897 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159488-A1 | APPLICATION OF HETEROCYCLIC COMPOUND CONTAINING AT LEAST TWO SULFUR ATOMS IN PREPARING NANO-VACCINE AND PREPARED NANO-VACCINE | Suzhou WEAST Biotechnology Co., Ltd. (CN) | 2023-05-25 | — | — | US | disclosed |
| US-20230159488-A1 | APPLICATION OF HETEROCYCLIC COMPOUND CONTAINING AT LEAST TWO SULFUR ATOMS IN PREPARING NANO-VACCINE AND PREPARED NANO-VACCINE | Suzhou WEAST Biotechnology Co., Ltd. (CN) | 2023-05-25 | — | — | US | disclosed |
| US-20170135926-A1 | TOPICAL COMPOSITIONS AND METHODS FOR SKIN LIGHTENING | AVON PROD INC (US) | 2017-05-18 | — | — | US | disclosed |
| US-20170135926-A1 | TOPICAL COMPOSITIONS AND METHODS FOR SKIN LIGHTENING | AVON PROD INC (US) | 2017-05-18 | — | — | US | disclosed |
| US-9592186-B2 | Topical compositions and methods for skin lightening | AVON PRODUCTS, INC. (US) | 2017-03-14 | — | — | US | disclosed |
| US-9566224-B2 | Tyrosinase inhibitors | AVON PRODUCTS, INC. (US) | 2017-02-14 | — | — | US | disclosed |
| US-9566224-B2 | Tyrosinase inhibitors | AVON PRODUCTS, INC. (US) | 2017-02-14 | — | — | US | disclosed |
| US-20160263006-A1 | TOPICAL COMPOSITIONS AND METHODS FOR SKIN LIGHTENING | AVON PRODUCTS, INC. | 2016-09-15 | — | — | US | disclosed |
| US-9364405-B2 | Tyrosinase inhibitors | AVON PRODUCTS, INC. (US) | 2016-06-14 | — | — | US | disclosed |
| US-9289364-B2 | Tyrosinase inhibitors | AVON PRODUCTS, INC. (US) | 2016-03-22 | — | — | US | disclosed |
| US-20150164758-A1 | TYROSINASE INHIBITORS | CITIBANK, N.A., LONDON BRANCH | 2015-06-18 | — | — | US | disclosed |
| US-20150152122-A1 | TYROSINASE INHIBITORS | AVON PRODUCTS, INC. | 2015-06-04 | — | — | US | disclosed |
| US-20150118170-A1 | TYROSINASE INHIBITORS | AVON PRODUCTS, INC. | 2015-04-30 | — | — | US | disclosed |
| US-20150111897-A1 | TYROSINASE INHIBITORS | NEW AVON LLC | 2015-04-23 | — | — | US | disclosed |
| US-8394427-B2 | Paxillin stimulating compositions and cosmetic uses thereof | AVON PRODUCTS, INC. (US) | 2013-03-12 | — | — | US | disclosed |
| US-20120328546-A1 | Paxillin Stimulating Compositions and Cosmetic Uses Thereof | AVON PRODUCTS, INC. (US) | 2012-12-27 | — | — | US | disclosed |
| US-8198390-B2 | Self assembled grafted polymeric layer for use in biosensor technology | IMEC (BE) | 2012-06-12 | — | — | US | disclosed |
| US-8168212-B2 | Topical compositions comprising non-proteogenic amino acids and methods of treating skin | AVON PRODUCTS, INC (US) | 2012-05-01 | — | — | US | disclosed |
| US-20110151029-A1 | Paxillin Stimulating Compositions and Cosmetic Uses Thereof | AVON PRODUCTS, INC. (US) | 2011-06-23 | — | — | US | disclosed |
| US-20100261769-A1 | Topical Compositions Comprising Non-Proteogenic Amino Acids and Methods of Treating Skin | AVON PRODUCTS, INC. (US) | 2010-10-14 | — | — | US | disclosed |