Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 12/20 | 0.46 |
| ▸ | ESR1 | P03372 | 11/20 | 0.46 |
| ▸ | PPARA | Q07869 | 6/20 | 0.43 |
| ▸ | PPARG | P37231 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18095717 | 0.88 | PPARG (0.46) | PPARAPPARGNPC1RAB9ATARBP2 | |
| SCHEMBL18095687 | 0.88 | PPARG (0.54) | PPARAPPARGNPC1RAB9ATARBP2 | |
| SCHEMBL6608776 | 0.87 | PPARG (0.42) | PPARAPPARGNPC1RAB9ATARBP2 | |
| SCHEMBL6603331 | 0.86 | PPARA (0.47) | PPARAPPARGNPC1RAB9ATARBP2 | |
| SCHEMBL18103290 | 0.84 | TARBP2 (0.56) | PPARAPPARGNPC1RAB9ATARBP2 | |
| SCHEMBL4478993 | 0.83 | PPARG (0.44) | PPARAPPARGPPARD | |
| SCHEMBL9910120 | 0.83 | PPARG (0.43) | ESR2ESR1PPARAPPARGNPC1 | |
| SCHEMBL4065595 | 0.80 | PPARG (0.44) | PPARAPPARGTARBP2PPARDHDAC6 | |
| SCHEMBL6607542 | 0.78 | PPARG (0.46) | PPARAPPARGNPC1RAB9ATARBP2 | |
| SCHEMBL6604633 | 0.78 | PPARG (0.47) | PPARAPPARGNPC1RAB9ATARBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012074980-A2 | METHODS OF TREATING OR PREVENTING AUTOIMMUNE DISORDERS AND LIVER DISORDERS USING INDANE ACETIC ACID DERIVATIVES | DARA BIOSCIENCES, INC. (US) | 2012-06-07 | — | — | WO | disclosed |