SCHEMBL9910786

SCHEMBL9910786

CCCCN(/C=C/C1=[N+](CCC(C)C)c2ccc(C(F)(F)F)cc2C1(C)C)CCCC

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.35
MAPT P10636 1/20 0.35
PRMT5 O14744 1/20 0.32
CARM1 Q86X55 1/20 0.32
PRMT1 Q99873 1/20 0.32
PRMT8 Q9NR22 1/20 0.32
CACNA1F O60840 1/20 0.31
CACNA1D Q01668 1/20 0.31
SLC6A3 Q01959 1/20 0.31
KCNH2 Q12809 1/20 0.31
CACNA1S Q13698 1/20 0.31
CACNA1C Q13936 1/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
HSP90AA1 P07900 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9910795 0.88 APP (0.31) APPMAPT
SCHEMBL9910790 0.86 CACNA1F (0.31) CACNA1FCACNA1DSLC6A3KCNH2CACNA1S
SCHEMBL10096760 0.80 APP (0.30) APPMAPT
SCHEMBL10096752 0.79 GAA (0.32) APPMAPT
SCHEMBL9910789 0.74 ALDH1A1 (0.34) PRMT1LMNA
SCHEMBL14184790 0.73 FURIN (0.38) MAPTPRMT1LMNA
SCHEMBL9910799 0.72 DRD2 (0.36) APPMAPTPRMT1
SCHEMBL11911120 0.72 PRMT1 (0.51) MAPTPRMT5CARM1PRMT1PRMT8
SCHEMBL13645491 0.71 APP (0.38) APPMAPTPRMT5CARM1PRMT1
SCHEMBL11953165 0.70 PRMT1 (0.48) MAPTPRMT5CARM1PRMT1PRMT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8197923-B2 Optical recording medium ADEKA CORPORATION (JP) 2012-06-12 US disclosed
EP-2360694-A1 Optical recording medium Adeka Corporation (JP) 2011-08-24 EP disclosed
EP-2002986-A9 OPTICAL RECORDING MEDIUM Adeka Corporation (JP) 2009-04-15 EP disclosed
US-20090029088-A1 OPTICAL RECORDING MEDIUM ADEKA CORPORATION (JP) 2009-01-29 US disclosed
EP-2002986-A2 OPTICAL RECORDING MEDIUM Adeka Corporation (JP) 2008-12-17 EP disclosed