⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8339214 | 0.78 | LMNA (0.40) | — | |
| SCHEMBL8790444 | 0.77 | CA2 (0.43) | — | |
| SCHEMBL8789737 | 0.73 | CA2 (0.56) | — | |
| SCHEMBL777041 | 0.72 | CA2 (0.48) | — | |
| SCHEMBL42358 | 0.72 | — | — | |
| SCHEMBL78146 | 0.72 | — | — | |
| SCHEMBL23699572 | 0.69 | LMNA (0.36) | — | |
| SCHEMBL8844939 | 0.69 | CA2 (0.52) | — | |
| SCHEMBL2781656 | 0.69 | — | — | |
| SCHEMBL8339213 | 0.69 | CA2 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020016468-A1 | PESTICIDAL 1-ARYLPYRAZOLE DERIVATIVES | RHONE-POULENC AGROCHIMIE (FR) | 2002-02-07 | — | — | US | claimed |
| EP-0948487-A1 | PESTICIDAL 1-ARYL AND PYRIDYLPYRAZOLE DERIVATIVES | RHONE-POULENC AGROCHIMIE (FR) | 1999-10-13 | — | — | EP | claimed |
| WO-1998028279-A1 | PESTICIDAL 1-ARYL AND PYRIDYLPYRAZOLE DERIVATIVES | RHONE-POULENC AGROCHIMIE (FR) | 1998-07-02 | — | — | WO | claimed |
| US-5691333-A | APPLYING TO CONTROL ARTHROPODS AND NEMATODES | RHONE-POULENC INC. (US) | 1997-11-25 | — | — | US | claimed |
| US-5629335-A | Pesticidal 1-arylpyrazole-3-carboximidothioic acid esters | RHONE-POULENC INC. (US) | 1997-05-13 | — | — | US | claimed |
| US-9139594-B2 | Fused aminodihydropyrimidone derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |
| EP-2233474-B1 | CONDENSED AMINODIHYDROTHIAZINE DERIVATIVE | EISAI R&D MAN CO LTD (JP) | 2015-08-05 | — | — | EP | disclosed |
| US-9079914-B2 | Fused aminodihydro-oxazine derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-07-14 | — | — | US | disclosed |
| EP-2332943-B1 | NOVEL FUSED AMINODIHYDROTHIAZINE DERIVATIVE | EISAI R&D MAN CO LTD (JP) | 2015-04-22 | — | — | EP | disclosed |
| US-8946210-B2 | Fused aminodihydrothiazine derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-02-03 | — | — | US | disclosed |
| US-8946211-B2 | Fused aminodihydrothiazine derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-02-03 | — | — | US | disclosed |
| WO-2014013076-A1 | HEXAHYDROPYRROLOTHIAZINE COMPOUNDS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2014-01-23 | — | — | WO | disclosed |
| WO-1998028279-A1 | PESTICIDAL 1-ARYL AND PYRIDYLPYRAZOLE DERIVATIVES | RHONE-POULENC AGROCHIMIE (FR) | 1998-07-02 | — | — | WO | disclosed |
| US-5691333-A | APPLYING TO CONTROL ARTHROPODS AND NEMATODES | RHONE-POULENC INC. (US) | 1997-11-25 | — | — | US | disclosed |
| WO-1997043280-A1 | 3-PHENYL-FURAN-(5H)-2-ONE AND DIHYDROFURAN-2-ONE DERIVATIVES AS ANTIBACTERIAL AGENTS | ZENECA LIMITED (GB) | 1997-11-20 | — | — | WO | disclosed |
| WO-1997030995-A1 | ANTIBIOTIC OXAZOLIDINONE DERIVATIVES | ZENECA LIMITED (GB) | 1997-08-28 | — | — | WO | disclosed |
| US-5629335-A | Pesticidal 1-arylpyrazole-3-carboximidothioic acid esters | RHONE-POULENC INC. (US) | 1997-05-13 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0392317-B1 | Benzimidazoles, drugs containing these compounds and process for their preparation | THOMAE GMBH DR K (DE) | 1996-01-03 | — | — | EP | disclosed |
| EP-0392317-A2 | Benzimidazoles, drugs containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1990-10-17 | — | — | EP | disclosed |