Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6706829 | 0.85 | SMN1; SMN2 (0.56) | RAB9AHPGDRECQLCA1CA2 | |
| SCHEMBL6706826 | 0.85 | SMN1; SMN2 (0.56) | RAB9AHPGDRECQLCA1CA2 | |
| SCHEMBL28818049 | 0.85 | CA1 (0.61) | RAB9AHPGDRECQLCA1CA2 | |
| SCHEMBL8117431 | 0.83 | RAB9A (0.61) | RAB9AHPGDRECQLCA1CA2 | |
| SCHEMBL11202027 | 0.83 | HTT (0.59) | RAB9AHPGDRECQLCA1CA2 | |
| SCHEMBL11202026 | 0.83 | HTT (0.59) | RAB9AHPGDRECQLCA1CA2 | |
| SCHEMBL11955708 | 0.82 | MEN1 (0.56) | RAB9AHPGDCA1CA2TSHR | |
| SCHEMBL12124929 | 0.82 | RAB9A (0.69) | RAB9AHPGDRECQLCA1CA2 | |
| SCHEMBL4416932 | 0.82 | RAB9A (0.52) | RAB9AHPGDRECQLCA1CA2 | |
| SCHEMBL11256349 | 0.82 | SMN1; SMN2 (0.59) | RAB9AHPGDRECQLSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10329258-B2 | CGAS in systemic lupus erythematosus (SLE) | UNIVERSITY OF WASHINGTON (US) | 2019-06-25 | — | — | US | disclosed |
| US-20180086713-A1 | CGAS IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) | UNIVERSITY OF WASHINGTON | 2018-03-29 | — | — | US | disclosed |
| US-20180086713-A1 | CGAS IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) | UNIVERSITY OF WASHINGTON | 2018-03-29 | — | — | US | disclosed |
| US-8198458-B2 | Non-nucleoside reverse transcriptase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-12 | — | — | US | disclosed |
| US-20090143370-A1 | Non-nucleoside Reverse Transcriptase Inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-06-04 | — | — | US | disclosed |
| US-7517998-B2 | Benzothiazole or benzothiazine derivative of dipyrido(2,3;b:2',3'-e) diazepin-6-one; viricide against human t-cell leukemia/lymphoma virus | BOEHRINGER INGELHEIM INTERNATIONAL GMBH | 2009-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086713-A1 | CGAS IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) | STING1, IRF3, CGAS | RAB9A 1851/4885HPGD 2333/4885RECQL 27/4885 |
| US-10329258-B2 | CGAS in systemic lupus erythematosus (SLE) | STING1, IRF3, CGAS | RAB9A 1851/4885HPGD 2333/4885RECQL 27/4885 |
| US-20090143370-A1 | Non-nucleoside Reverse Transcriptase Inhibitors | RTF1, POLR1A, POLR1E | RAB9A 3111/4885HPGD 826/4885RECQL 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.