SCHEMBL9911675

SCHEMBL9911675

COc1ccc2cc3cc(C=O)ccc3cc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.61
CYP2A6 P11509 2/20 0.61
CYP1A2 P05177 2/20 0.50
TSHR P16473 1/20 0.50
PTGER4 P35408 1/20 0.50
NQO2 P16083 2/20 0.47
MAOB P27338 1/20 0.47
TRIM24 O15164 2/20 0.46
TRIM33 Q9UPN9 2/20 0.46
ERN1 O75460 1/20 0.46
TYR P14679 1/20 0.46
KDM4E B2RXH2 1/20 0.46
GSTP1 P09211 1/20 0.46
RELA Q04206 1/20 0.46
AOX1 Q06278 1/20 0.46
HPGD P15428 1/20 0.46
ALDH5A1 P51649 1/20 0.46
ABAT P80404 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ESR1 P03372 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3154032 0.96 ALDH1A1 (0.61) ALDH1A1CYP2A6CYP1A2TSHRPTGER4
SCHEMBL271175 0.96 ALDH1A1 (0.65) ALDH1A1CYP2A6CYP1A2TSHRPTGER4
SCHEMBL29577162 0.96 ALDH1A1 (0.65) ALDH1A1CYP2A6CYP1A2TSHRPTGER4
SCHEMBL9616603 0.96 ALDH1A1 (0.65) ALDH1A1CYP2A6CYP1A2TSHRPTGER4
Hydrochloric Acid SCHEMBL28903002 0.94 ALDH1A1 (0.63) ALDH1A1CYP2A6CYP1A2TSHRPTGER4
Methane SCHEMBL28484734 0.94 ALDH1A1 (0.63) ALDH1A1CYP2A6CYP1A2TSHRPTGER4
SCHEMBL9883838 0.83 CYP2A6 (0.50) ALDH1A1CYP2A6TSHRKDM4ERELA
SCHEMBL19182196 0.83 CYP2A6 (0.50) ALDH1A1CYP2A6TSHRKDM4ERELA
SCHEMBL29617405 0.83 CYP2A6 (0.50) ALDH1A1CYP2A6TSHRKDM4ERELA
SCHEMBL30972495 0.83 CYP2A6 (0.50) ALDH1A1CYP2A6TSHRKDM4ERELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120142193-A1 RESIST UNDERLAYER FILM COMPOSITION AND PATTERNING PROCESS USING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-06-07 US disclosed
US-20110040069-A1 CONDENSED POLYCYCLIC COMPOUND, CONDENSED POLYCYCLIC POLYMER AND ORGANIC THIN FILM CONTAINING THE COMPOUND OR THE POLYMER OSAKA UNIVERSITY (JP) 2011-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110040069-A1 CONDENSED POLYCYCLIC COMPOUND, CONDENSED POLYCYCLIC POLYMER AND ORGANIC THIN FILM CONTAINING THE COMPOUND OR THE POLYMER SLC43A1, SLC7A5, SLCO2A1 ALDH1A1 3912/4885CYP2A6 4523/4885CYP1A2 3343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.