Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 8/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 2/20 | 0.37 |
| ▸ | BTK | Q06187 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | NRP1 | O14786 | 1/20 | 0.33 |
| ▸ | CD38 | P28907 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4490461 | 0.86 | PTGDR (0.69) | PTGDR | |
| SCHEMBL9912276 | 0.81 | PTGDR (0.63) | PTGDRADORA2AMMP3PIK3CAPIK3CB | |
| SCHEMBL9912199 | 0.78 | PTGDR (0.51) | PTGDRLCKBTKMAPK14CNR1 | |
| SCHEMBL4503611 | 0.76 | PTGDR (0.74) | PTGDR | |
| SCHEMBL13895069 | 0.74 | PTGDR (0.73) | PTGDR | |
| SCHEMBL4490256 | 0.73 | PTGDR (0.75) | PTGDRLCKBTKMAPK14 | |
| SCHEMBL4503117 | 0.72 | PTGDR (0.67) | PTGDR | |
| SCHEMBL13895066 | 0.72 | PTGDR (0.47) | PTGDRLCKBTKMAPK14PIK3CA | |
| SCHEMBL4504101 | 0.71 | PTGDR (0.66) | PTGDR | |
| SCHEMBL9911102 | 0.71 | PTGDR (0.65) | PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8193183-B2 | 2,6-substituted-4-monosubstitutedamino-pyrimidine as prostaglandin D2 receptor antagonists | AVENTIS PHARMACEUTICALS INC. (US) | 2012-06-05 | — | — | US | disclosed |