Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9612026 | 0.90 | LMNA (0.41) | LMNAALDH1A1MAPTMAPK1ALOX15 | |
| SCHEMBL861073 | 0.81 | SMN1; SMN2 (0.41) | LMNAALDH1A1MAPTMAPK1ALOX15 | |
| SCHEMBL15804409 | 0.63 | CYP4F2 (0.59) | LMNAALDH1A1MAPTMAPK1GAA | |
| SCHEMBL19889056 | 0.61 | SMN1; SMN2 (0.58) | LMNAALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL25242176 | 0.60 | MAPK8 (0.51) | SMN1; SMN2 | |
| SCHEMBL1107142 | 0.59 | CYP4F2 (0.66) | LMNAALDH1A1MAPTMAPK1GAA | |
| SCHEMBL4167413 | 0.59 | ALDH1A1 (0.58) | LMNAALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL31324186 | 0.59 | CYP4F2 (0.56) | LMNAALDH1A1MAPTMAPK1GAA | |
| Ammonia Solution, Strong SCHEMBL28854172 | 0.58 | CYP4F2 (0.63) | LMNAALDH1A1MAPTMAPK1GAA | |
| SCHEMBL13926073 | 0.58 | KLK7 (0.55) | LMNAALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198458-B2 | Non-nucleoside reverse transcriptase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-12 | — | — | US | disclosed |