Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | TACR2 | P21452 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9912503 | 0.85 | KMT2A (0.43) | KMT2ALMNAMEN1NR1I2AHR | |
| SCHEMBL9912553 | 0.82 | LMNA (0.41) | KMT2ALMNAMEN1CYP1A2CYP2C19 | |
| SCHEMBL9912498 | 0.71 | LMNA (0.41) | KMT2ALMNAMEN1CYP1A2CYP2C19 | |
| SCHEMBL9912581 | 0.71 | GAA (0.42) | KMT2AMAPT | |
| SCHEMBL9105291 | 0.69 | KMT2A (0.41) | KMT2ALMNAMEN1CYP1A2CYP2C19 | |
| SCHEMBL9106464 | 0.68 | KMT2A (0.39) | KMT2ALMNAMEN1NR1I2AHR | |
| Hydrochloric Acid SCHEMBL9105736 | 0.68 | KMT2A (0.40) | KMT2ALMNAMEN1CYP1A2CYP2C19 | |
| SCHEMBL9107690 | 0.68 | LMNA (0.43) | KMT2ALMNAMEN1CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL9102432 | 0.67 | LMNA (0.42) | KMT2ALMNAMEN1CYP1A2CYP2C19 | |
| SCHEMBL9912587 | 0.66 | KMT2A (0.38) | KMT2ALMNAMEN1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012074999-A1 | NOVEL COMPOUNDS AS RESPIRATORY STIMULANTS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES | GALLEON PHARMACEUTICALS, INC. (US) | 2012-06-07 | — | — | WO | disclosed |