Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9912552 | 0.85 | KMT2A (0.41) | KMT2ALMNAMEN1NR1I2AHR | |
| SCHEMBL9105291 | 0.82 | KMT2A (0.41) | KMT2ALMNAMEN1ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL9105736 | 0.81 | KMT2A (0.40) | KMT2ALMNAMEN1ALDH1A1GAA | |
| SCHEMBL9107690 | 0.81 | LMNA (0.43) | KMT2ALMNAMEN1ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL9102432 | 0.80 | LMNA (0.42) | KMT2ALMNAMEN1ALDH1A1GAA | |
| SCHEMBL9912587 | 0.79 | KMT2A (0.38) | KMT2ALMNAMEN1ALDH1A1GAA | |
| SCHEMBL9912498 | 0.79 | LMNA (0.41) | KMT2ALMNAMEN1ALDH1A1GAA | |
| SCHEMBL9108283 | 0.77 | MEN1 (0.40) | KMT2ALMNAMEN1ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL9106602 | 0.76 | MEN1 (0.39) | KMT2ALMNAMEN1ALDH1A1GAA | |
| SCHEMBL9101017 | 0.74 | LMNA (0.35) | KMT2ALMNAMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012074999-A1 | NOVEL COMPOUNDS AS RESPIRATORY STIMULANTS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES | GALLEON PHARMACEUTICALS, INC. (US) | 2012-06-07 | — | — | WO | disclosed |