Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 10/20 | 0.73 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21815483 | 0.99 | HRH1 (0.72) | HRH1KCNH2CHRM1KDM4EPDE10A | |
| Hydrochloric Acid SCHEMBL28374789 | 0.99 | HRH1 (0.72) | HRH1KCNH2CHRM1KDM4EPDE10A | |
| Tert-Butyl Formate SCHEMBL28758272 | 0.90 | HRH1 (0.61) | HRH1KCNH2CHRM1KDM4EPDE10A | |
| SCHEMBL14198337 | 0.88 | HRH1 (0.80) | HRH1KCNH2CHRM1KDM4EPDE10A | |
| SCHEMBL19770379 | 0.87 | HRH1 (0.95) | HRH1KCNH2 | |
| SCHEMBL7501591 | 0.86 | HRH1 (0.77) | HRH1KCNH2CHRM1KDM4EPDE10A | |
| SCHEMBL17898450 | 0.85 | HRH1 (1.00) | HRH1KCNH2CHRM1 | |
| SCHEMBL17895346 | 0.85 | HRH1 (0.87) | HRH1KCNH2 | |
| SCHEMBL19770377 | 0.84 | HRH1 (0.85) | HRH1KCNH2 | |
| Hydrochloric Acid SCHEMBL30881897 | 0.83 | JAK2 (0.53) | HRH1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129039-A1 | NOVEL PROCESS FOR THE PREPARATION OF BILASTINE AND INTERMEDIATES THEREOF | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2025-04-24 | — | — | US | claimed |
| CN-118961946-A | Method for detecting residual impurities in bilastine | 石家庄四药有限公司 | 2024-11-15 | — | — | CN | claimed |
| WO-2023037184-A2 | NOVEL PROCESS FOR THE PREPARATION OF BILASTINE AND INTERMEDIATES THEREOF | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD (IN) | 2023-03-16 | — | — | WO | claimed |
| CN-108711632-B | Anion exchange membrane for fuel cell and preparation method thereof | 天朤(江苏)氢能源科技有限公司 | 2021-03-26 | — | — | CN | claimed |
| CN-111689953-A | Preparation method of bilastine intermediate | 北京万全德众医药生物技术有限公司 | 2020-09-22 | — | — | CN | claimed |
| CN-106146459-B | Preparation method of bilastine | 山东罗欣药业集团恒欣药业有限公司 | 2019-12-20 | — | — | CN | claimed |
| CN-109081827-A | A kind of preparation method and application of bilastine | 北京天弘天达医药科技股份有限公司 | 2018-12-25 | — | — | CN | claimed |
| WO-2018042305-A1 | IMPROVED PROCESSES FOR PREPARATION OF BILASTINE USING NOVEL INTERMEDIATES | SYMED LABS LIMITED (IN) | 2018-03-08 | — | — | WO | claimed |
| CN-106146459-A | A kind of preparation method of bilastine | 山东罗欣药业集团恒欣药业有限公司 | 2016-11-23 | — | — | CN | claimed |
| CN-114591292-B | Bilastine intermediate compounds | 鲁南制药集团股份有限公司 | 2025-06-17 | — | — | CN | disclosed |
| CN-114591291-B | Bilastine intermediate compound and preparation method thereof | 鲁南制药集团股份有限公司 | 2025-06-17 | — | — | CN | disclosed |
| CN-114591292-B | Bilastine intermediate compounds | 鲁南制药集团股份有限公司 | 2025-06-17 | — | — | CN | disclosed |
| US-20250129039-A1 | NOVEL PROCESS FOR THE PREPARATION OF BILASTINE AND INTERMEDIATES THEREOF | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2025-04-24 | — | — | US | disclosed |
| CN-118961946-A | Method for detecting residual impurities in bilastine | 石家庄四药有限公司 | 2024-11-15 | — | — | CN | disclosed |
| US-8367704-B2 | Process for preparation of 2-methyl-2′ phenylpropionic acid derivatives and novel intermediate compounds | YUHAN CORPORATION (KR) | 2013-02-05 | — | — | US | disclosed |
| US-20110009636-A1 | PROCESS FOR THE PREPARATION OF 2-METHYL-2'-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS | YUHAN CORPORATION (KP) | 2011-01-13 | — | — | US | disclosed |
| EP-2240464-A2 | PROCESS FOR PREPARATION OF 2-METHYL-2´-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS | Yuhan Corporation (KR) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009102155-A2 | PROCESS FOR PREPARATION OF 2-METHYL-2´-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS | YUHAN CORPORATION (KR) | 2009-08-20 | — | — | WO | disclosed |
| US-7235538-B2 | Heterocyclic compounds, which are inhibitors of the enzyme DPP-IV | NOVO NORDISK A/S (DK) | 2007-06-26 | — | — | US | disclosed |
| US-7235538-B2 | Heterocyclic compounds, which are inhibitors of the enzyme DPP-IV | NOVO NORDISK A/S (DK) | 2007-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009636-A1 | PROCESS FOR THE PREPARATION OF 2-METHYL-2'-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS | HRH4, HCAR2, HRH1 | HRH1 3/4885KCNH2 945/4885CHRM1 211/4885 |
| US-20250129039-A1 | NOVEL PROCESS FOR THE PREPARATION OF BILASTINE AND INTERMEDIATES THEREOF | CYP4B1, CYP3A4, CYP7A1 | HRH1 15/4885KCNH2 1118/4885CHRM1 833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.