SCHEMBL9912926

SCHEMBL9912926

Cc1ccc(N(c2cccc(-n3c4ccc(N(c5ccc(C)cc5)c5ccc6ccccc6c5)cc4c4cc(N(c5ccc(C)cc5)c5ccc6ccccc6c5)ccc43)c2)c2ccc3ccccc3c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TDP1 Q9NUW8 2/20 0.37
CYP2A6 P11509 1/20 0.37
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35
OPRD1 P41143 1/20 0.33
HTR2C P28335 5/20 0.33
HTR2A P28223 4/20 0.33
DRD3 P35462 4/20 0.33
HTR6 P50406 4/20 0.33
HTR1A P08908 3/20 0.33
HTR7 P34969 3/20 0.33
ALDH1A1 P00352 3/20 0.32
LMNA P02545 2/20 0.32
GAA P10253 1/20 0.32
EGFR P00533 1/20 0.32
ERBB2 P04626 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9912921 0.92 LMNA (0.39) HTTNPSR1L3MBTL1TDP1CYP2A6
SCHEMBL9912923 0.92 KDM4E (0.36) HTTNPSR1L3MBTL1TDP1OPRD1
SCHEMBL9912951 0.91 HTT (0.39) HTTNPSR1L3MBTL1TDP1CYP2A6
SCHEMBL9912902 0.91 HTT (0.42) HTTNPSR1L3MBTL1TDP1CYP2A6
SCHEMBL9912915 0.91 KDM4E (0.37) HTTNPSR1L3MBTL1TDP1ALDH1A1
SCHEMBL9912940 0.91 POLB (0.34) HTTNPSR1L3MBTL1HTR2CALDH1A1
SCHEMBL14564969 0.90 CYP2A6 (0.40) HTTNPSR1L3MBTL1TDP1CYP2A6
SCHEMBL9912929 0.88 CYP1A2 (0.40) HTTNPSR1L3MBTL1TDP1CYP2A6
SCHEMBL14564957 0.87 CYP2A6 (0.40) HTTNPSR1L3MBTL1TDP1CYP2A6
SCHEMBL9912899 0.87 MAPT (0.39) HTTNPSR1L3MBTL1TDP1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8198801-B2 Materials for injecting or transporting holes and organic electroluminescence devices using the same LG CHEM, LTD. (KR) 2012-06-12 US disclosed
US-8198801-B2 Materials for injecting or transporting holes and organic electroluminescence devices using the same LG CHEM, LTD. (KR) 2012-06-12 US disclosed