SCHEMBL9912951

SCHEMBL9912951

Cc1ccc(N(c2cc(N(c3ccccc3)c3ccc4ccccc4c3)cc(-n3c4ccc(N(c5ccc(C)cc5)c5ccc6ccccc6c5)cc4c4cc(N(c5ccc(C)cc5)c5ccc6ccccc6c5)ccc43)c2)c2ccc3ccccc3c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.39
NPSR1 Q6W5P4 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CYP2A6 P11509 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
APP P05067 1/20 0.33
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
EGFR P00533 1/20 0.31
ERBB2 P04626 1/20 0.31
ERBB3 P21860 1/20 0.31
KDR P35968 1/20 0.31
PTK2 Q05397 1/20 0.31
MAPT P10636 3/20 0.31
ALDH1A1 P00352 3/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
KDM4E B2RXH2 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9912943 0.94 KDM4E (0.33) L3MBTL1TDP1MAPTALDH1A1KDM4E
SCHEMBL9912945 0.92 APP (0.37) HTTNPSR1L3MBTL1TDP1APP
SCHEMBL9912926 0.91 HTT (0.39) HTTNPSR1L3MBTL1CYP2A6TDP1
SCHEMBL9912949 0.90 TDP1 (0.38) HTTNPSR1L3MBTL1CYP2A6TDP1
SCHEMBL9912902 0.90 HTT (0.42) HTTNPSR1L3MBTL1CYP2A6TDP1
SCHEMBL14564969 0.89 CYP2A6 (0.40) HTTNPSR1L3MBTL1CYP2A6TDP1
SCHEMBL15595253 0.88 KDM4E (0.41) HTTNPSR1L3MBTL1TDP1APP
SCHEMBL15595166 0.88 KDM4E (0.41) HTTNPSR1L3MBTL1TDP1APP
SCHEMBL15595174 0.88 APP (0.36) HTTNPSR1L3MBTL1TDP1APP
SCHEMBL9912960 0.87 POLB (0.35) MAPTALDH1A1KDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8198801-B2 Materials for injecting or transporting holes and organic electroluminescence devices using the same LG CHEM, LTD. (KR) 2012-06-12 US disclosed
US-8198801-B2 Materials for injecting or transporting holes and organic electroluminescence devices using the same LG CHEM, LTD. (KR) 2012-06-12 US disclosed