SCHEMBL9912943

SCHEMBL9912943

c1ccc(N(c2cc(N(c3ccccc3)c3ccc4ccccc4c3)cc(-n3c4ccc(N(c5ccccc5)c5ccc6ccccc6c5)cc4c4cc(N(c5ccccc5)c5ccc6ccccc6c5)ccc43)c2)c2ccc3ccccc3c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
ALDH1A1 P00352 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ATM Q13315 1/20 0.33
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
PER2 O15055 1/20 0.30
CRY1 Q16526 1/20 0.30
CRY2 Q49AN0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9912951 0.94 HTT (0.39) KDM4EL3MBTL1ALDH1A1CYP1A2CYP3A4
SCHEMBL9912923 0.91 KDM4E (0.36) KDM4EL3MBTL1ALDH1A1CYP1A2CYP3A4
SCHEMBL9912967 0.91 KDM4E (0.38) KDM4EL3MBTL1ALDH1A1CYP1A2CYP3A4
SCHEMBL9912979 0.91 KDM4E (0.38) KDM4EL3MBTL1ALDH1A1CYP1A2CYP3A4
SCHEMBL12559426 0.91 KDM4E (0.42) KDM4EL3MBTL1ALDH1A1CYP1A2CYP3A4
SCHEMBL9912866 0.91 KDM4E (0.38) KDM4EL3MBTL1ALDH1A1CYP1A2CYP3A4
SCHEMBL12559427 0.91 KDM4E (0.42) KDM4EL3MBTL1ALDH1A1CYP1A2CYP3A4
SCHEMBL9912941 0.91 L3MBTL1 (0.38) KDM4EL3MBTL1ALDH1A1CYP1A2CYP3A4
SCHEMBL13341838 0.90 HSP90AA1 (0.35) KDM4EL3MBTL1ALDH1A1CYP1A2CYP3A4
SCHEMBL12856876 0.90 KDM4E (0.43) KDM4EL3MBTL1ALDH1A1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8198801-B2 Materials for injecting or transporting holes and organic electroluminescence devices using the same LG CHEM, LTD. (KR) 2012-06-12 US disclosed
US-8198801-B2 Materials for injecting or transporting holes and organic electroluminescence devices using the same LG CHEM, LTD. (KR) 2012-06-12 US disclosed