Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10637125 | 0.87 | CYP3A4 (0.48) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL24073998 | 0.79 | HSD17B10 (0.33) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL687110 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL256203 | 0.77 | ALDH1A1 (0.64) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL29377581 | 0.77 | ALDH1A1 (0.64) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL30001931 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL43313 | 0.75 | MAPK1 (0.46) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL4191021 | 0.75 | HSD17B10 (0.36) | ALDH1A1MAPTCYP3A4HSD17B10RAB9A | |
| SCHEMBL779949 | 0.75 | ALDH1A1 (0.50) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL8878556 | 0.75 | ALDH1A1 (0.61) | ALDH1A1MAPTMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012075381-A1 | SUBSTITUTED PURINE AND 7 - DEAZAPURINE COMPOUNDS AS MODULATORS OF EPIGENETIC ENZYMES | Epizyme, Inc. (US) | 2012-06-07 | — | — | WO | disclosed |