Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PYGB | P11216 | 1/20 | 0.43 |
| ▸ | CD69 | Q07108 | 1/20 | 0.43 |
| ▸ | LGALS3 | P17931 | 5/20 | 0.41 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.40 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.40 |
| ▸ | LGALS7; LGALS7B | P47929 | 2/20 | 0.40 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14025388 | 1.00 | ALDH1A1 (0.57) | ALDH1A1THRBMAPK1SMN1; SMN2PYGB | |
| SCHEMBL18102361 | 0.89 | ALDH1A1 (0.63) | ALDH1A1THRBMAPK1SMN1; SMN2PYGB | |
| SCHEMBL11946954 | 0.89 | ALDH1A1 (0.63) | ALDH1A1THRBMAPK1SMN1; SMN2PYGB | |
| SCHEMBL9914082 | 0.89 | ALDH1A1 (0.63) | ALDH1A1THRBMAPK1SMN1; SMN2PYGB | |
| SCHEMBL14025370 | 0.89 | ALDH1A1 (0.63) | ALDH1A1THRBMAPK1SMN1; SMN2PYGB | |
| SCHEMBL22311649 | 0.89 | ALDH1A1 (0.63) | ALDH1A1THRBMAPK1SMN1; SMN2PYGB | |
| SCHEMBL18708293 | 0.89 | ALDH1A1 (0.63) | ALDH1A1THRBMAPK1SMN1; SMN2PYGB | |
| SCHEMBL22311199 | 0.89 | ALDH1A1 (0.63) | ALDH1A1THRBMAPK1SMN1; SMN2PYGB | |
| SCHEMBL22311210 | 0.89 | ALDH1A1 (0.63) | ALDH1A1THRBMAPK1SMN1; SMN2PYGB | |
| SCHEMBL14051305 | 0.89 | ALDH1A1 (0.63) | ALDH1A1THRBMAPK1SMN1; SMN2PYGB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120264924-A1 | Glycorandomization and Production of Novel Novobiocin Analogs | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-10-18 | — | — | US | disclosed |
| US-8198419-B2 | Glycorandomization and production of novel erythromycin analogs | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-06-12 | — | — | US | disclosed |
| US-20110124850-A1 | Glycorandomization and Production of Novel Vancomycin Analogs | THORSON JON | 2011-05-26 | — | — | US | disclosed |
| US-7348309-B2 | Glycorandomization and production of novel vancomycin analogs | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124850-A1 | Glycorandomization and Production of Novel Vancomycin Analogs | NMT1, NMT2, B3GNT2 | ALDH1A1 1950/4885THRB 4071/4885MAPK1 4161/4885 |
| US-20120264924-A1 | Glycorandomization and Production of Novel Novobiocin Analogs | NMT2, NMT1, NAMPT | ALDH1A1 2259/4885THRB 4386/4885MAPK1 4166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.