Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.67 |
| ▸ | NPC1 | O15118 | 7/20 | 0.67 |
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.55 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.53 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.53 |
| ▸ | TOP2A | P11388 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2161944 | 0.80 | NPC1 (1.00) | RAB9ANPC1MAPTALDH1A1PLA2G1B | |
| SCHEMBL10372230 | 0.80 | NPC1 (0.67) | RAB9ANPC1MAPTALDH1A1PLA2G1B | |
| SCHEMBL5665680 | 0.80 | NPC1 (1.00) | RAB9ANPC1MAPTALDH1A1PLA2G1B | |
| SCHEMBL2161942 | 0.80 | NPC1 (1.00) | RAB9ANPC1MAPTALDH1A1PLA2G1B | |
| SCHEMBL12756981 | 0.79 | RAB9A (0.61) | RAB9ANPC1MAPTALDH1A1PLA2G1B | |
| SCHEMBL4335201 | 0.78 | NPC1 (0.65) | RAB9ANPC1MAPTALDH1A1PLA2G1B | |
| Water SCHEMBL10376517 | 0.78 | NPC1 (0.65) | RAB9ANPC1MAPTALDH1A1PLA2G1B | |
| Water SCHEMBL10376519 | 0.78 | NPC1 (0.65) | RAB9ANPC1MAPTALDH1A1PLA2G1B | |
| SCHEMBL4254487 | 0.78 | NPC1 (0.65) | RAB9ANPC1MAPTALDH1A1PLA2G1B | |
| SCHEMBL4254489 | 0.78 | NPC1 (0.65) | RAB9ANPC1MAPTALDH1A1PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8197847-B2 | Process for making polymers and supports comprising pendant sugar side groups | WARWICK EFFECT POLYMERS LTD. (GB) | 2012-06-12 | — | — | US | disclosed |
| US-20090082224-A1 | POLYMERS | WARWICK EFFECT POLYMERS LIMITED (GB) | 2009-03-26 | — | — | US | disclosed |
| US-7498398-B2 | Thermoplastic composition, method of making, and articles formed therefrom | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2009-03-03 | — | — | US | disclosed |
| US-20070225470-A1 | Thermoplastic composition, method of making, and articles formed therefrom | SABIC GLOBAL TECHNOLOGIES IP B.V. (NL) | 2007-09-27 | — | — | US | disclosed |
| US-20070219330-A1 | Amide initiators | WARWICK EFFECT POLYMERS LIMITED (GB) | 2007-09-20 | — | — | US | disclosed |