Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 1.00 |
| ▸ | RAB9A | P51151 | 6/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.53 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.53 |
| ▸ | TOP2A | P11388 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | ECE2 | P0DPD6 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5665680 | 1.00 | NPC1 (1.00) | NPC1RAB9AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL2161942 | 1.00 | NPC1 (1.00) | NPC1RAB9AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10372230 | 0.80 | NPC1 (0.67) | NPC1RAB9AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL9914145 | 0.80 | RAB9A (0.67) | NPC1RAB9AKDM4EALDH1A1CYP1A2 | |
| Water SCHEMBL10376517 | 0.78 | NPC1 (0.65) | NPC1RAB9AKDM4EALDH1A1CYP1A2 | |
| Water SCHEMBL10376519 | 0.78 | NPC1 (0.65) | NPC1RAB9AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL4254487 | 0.78 | NPC1 (0.65) | NPC1RAB9AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL4335201 | 0.78 | NPC1 (0.65) | NPC1RAB9AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL4254489 | 0.78 | NPC1 (0.65) | NPC1RAB9AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL31241393 | 0.77 | ALDH1A1 (0.67) | NPC1RAB9AKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1527165-A4 | A RHODOCOCCUS GENE ENCODING ALDOXIME DEHYDRATASE | DU PONT (US) | 2006-06-07 | — | — | EP | claimed |
| EP-1527165-A2 | A RHODOCOCCUS GENE ENCODING ALDOXIME DEHYDRATASE | E.I. du Pont de Nemours and Company (US) | 2005-05-04 | — | — | EP | claimed |
| US-20030215929-A1 | Rhodococcus gene encoding aldoxime dehydratase | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-11-20 | — | — | US | claimed |
| WO-2003078581-A2 | A RHODOCOCCUS GENE ENCODING ALDOXIME DEHYDRATASE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-09-25 | — | — | WO | claimed |
| US-12570675-B2 | Boronic acid compounds | LG CHEM, LTD. (KR) | 2026-03-10 | — | — | US | disclosed |
| US-20260027102-A1 | QUINOLYLNITRONE DERIVATIVES FOR USE IN THE PREVENTION AND/OR TREATMENT OF HEARING LOSS | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) | 2026-01-29 | — | — | US | disclosed |
| EP-4558144-A1 | QUINOLYLNITRONE DERIVATIVES FOR USE IN THE PREVENTION AND/OR TREATMENT OF HEARING LOSS | Consejo Superior De Investigaciones Científicas - CSIC (ES) | 2025-05-28 | — | — | EP | disclosed |
| US-20240101579-A1 | BORONIC ACID COMPOUNDS | LG CHEM, LTD. (KR) | 2024-03-28 | — | — | US | disclosed |
| WO-2024018073-A1 | QUINOLYLNITRONE DERIVATIVES FOR USE IN THE PREVENTION AND/OR TREATMENT OF HEARING LOSS | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) | 2024-01-25 | — | — | WO | disclosed |
| EP-4309655-A1 | QUINOLYLNITRONE DERIVATIVES FOR USE IN THE PREVENTION AND/OR TREATMENT OF HEARING LOSS | Consejo Superior de Investigaciones Científicas (CSIC) (ES) | 2024-01-24 | — | — | EP | disclosed |
| EP-4242213-A1 | BORONIC ACID COMPOUND | Lg Chem, Ltd. (KR) | 2023-09-13 | — | — | EP | disclosed |
| CN-116568310-A | Boric acid compounds | 株式会社LG化学 | 2023-08-08 | — | — | CN | disclosed |
| US-5789138-A | Optical recording medium and method of producing the same | RICOH COMPANY, LTD. (JP) | 1998-08-04 | — | — | US | disclosed |
| US-5780490-A | A O-(2,4-OXA(OR THIA)ZOLIDINYL)PHENYLOXY(OR THIO OR AMINO) ALKYLOXIME; ALDOSE REDUCTASE INHIBITORS; ANTIDIABETIC AND -HYPOGLYCEMIC AGENTS; LIVER, SKIN AND UROGENITAL DISORDERS | SANKYO COMPANY, LIMITED (JP) | 1998-07-14 | — | — | US | disclosed |
| US-5703096-A | ANTIDIABETIC AGENTS; ALDOSE REDUCTASE INHIBITOR | SANKYO COMPANY, LIMITED (JP) | 1997-12-30 | — | — | US | disclosed |
| CN-1143639-A | Oxime derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1997-02-26 | — | — | CN | disclosed |
| EP-0708098-A1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-4450270-A | Dioximino cephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1984-05-22 | — | — | US | disclosed |
| US-4402955-A | ZWITTERIONS; GRAMNEGATIVE BACTERIA | ELI LILLY AND COMPANY (US) | 1983-09-06 | — | — | US | disclosed |
| US-4379787-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1983-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12570675-B2 | Boronic acid compounds | PSMB6, PSMB3, PSMB2 | NPC1 208/4885RAB9A 715/4885KDM4E 3458/4885 |
| US-20240101579-A1 | BORONIC ACID COMPOUNDS | PSMB11, PSMB1, BACH1 | NPC1 180/4885RAB9A 931/4885KDM4E 2004/4885 |
| US-20260027102-A1 | QUINOLYLNITRONE DERIVATIVES FOR USE IN THE PREVENTION AND/OR TREATMENT OF HEARING LOSS | CYC1, MT-CO1, MT-ND1 | NPC1 332/4885RAB9A 1868/4885KDM4E 3678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.