SCHEMBL9914231

SCHEMBL9914231

COc1cc(C)ccc1SC

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.58
ALDH1A1 P00352 4/20 0.47
CYP3A4 P08684 1/20 0.47
KMT2A Q03164 3/20 0.46
HTR1A P08908 2/20 0.43
HTR3A P46098 2/20 0.43
ALOX15 P16050 3/20 0.42
MAPT P10636 3/20 0.42
HPGD P15428 3/20 0.42
MAPK1 P28482 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
GAA P10253 2/20 0.42
HSD17B10 Q99714 2/20 0.42
ATM Q13315 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MEN1 O00255 2/20 0.41
ALOX12 P18054 2/20 0.41
USP2 O75604 1/20 0.41
POLB P06746 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13294876 0.84 ACHE (0.60) ACHEALDH1A1CYP3A4KMT2AALOX15
SCHEMBL23912787 0.81 ACHE (0.56) ACHEALDH1A1CYP3A4KMT2AHTR1A
SCHEMBL3511278 0.78 CA12 (0.58) ALDH1A1CYP3A4KMT2AMAPTHPGD
SCHEMBL16954273 0.78 MAPT (0.45) ACHEALDH1A1KMT2AALOX15MAPT
SCHEMBL31345541 0.78 MAPT (0.63) ACHEALDH1A1CYP3A4KMT2AHTR1A
SCHEMBL26717551 0.78 ACHE (0.52) ACHEALDH1A1CYP3A4KMT2AHTR1A
SCHEMBL5746669 0.77 MAOB (0.57) ALDH1A1CYP3A4KMT2AALOX15MAPT
SCHEMBL31050347 0.77 KDM4E (0.40) ALOX15L3MBTL1ATMTDP1POLB
SCHEMBL11356993 0.77 MAPT (0.52) ALDH1A1CYP3A4ALOX15MAPTMAPK1
SCHEMBL833974 0.77 KDM4E (0.40) ALOX15L3MBTL1ATMTDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357507-A1 SULFUR-CONTAINING POLYMER, METHOD FOR PRODUCING SAME, AND SULFUR-CONTAINING POLYMER COMPOSITION NIPPON SHOKUBAI CO., LTD. (JP) 2023-11-09 US disclosed
EP-4220242-A1 SULFUR-CONTAINING POLYMER, METHOD FOR PRODUCING SAME, AND SULFUR-CONTAINING POLYMER COMPOSITION Nippon Shokubai Co., Ltd. (JP) 2023-08-02 EP disclosed
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed
US-8198205-B2 Aromatic block copolymer, decomposition method thereof and analysis method using the decomposition method SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-06-12 US disclosed
US-20110081597-A1 POLYMER ELECTROLYTE, CROSSLINKED POLYMER ELECTROLYTE, POLYMER ELECTROLYTE MEMBRANE AND USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-07 US disclosed
US-20100239947-A1 Condensed ring-containing polymer electrolyte and application thereof SUMITOMO CHEMICAL COMPANY, LIMITED 2010-09-23 US disclosed
US-20090197763-A1 Aromatic block copolymer, decomposition method thereof and analysis method using the decomposition method SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-08-06 US disclosed