SCHEMBL9914237

SCHEMBL9914237

COc1ccc(C(=O)c2ccc(C)c(C)c2)cc1C

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.63
CYP2C19 P33261 2/20 0.63
CYP3A4 P08684 1/20 0.63
CYP2C9 P11712 1/20 0.63
TSHR P16473 1/20 0.63
HTT P42858 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
ALDH1A1 P00352 6/20 0.58
LMNA P02545 3/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
SLC22A6 Q4U2R8 1/20 0.55
SLC22A8 Q8TCC7 1/20 0.55
GAA P10253 1/20 0.54
NPC1 O15118 1/20 0.53
MITF O75030 1/20 0.53
POLB P06746 1/20 0.53
MAPT P10636 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
TUBB4A P04350 3/20 0.50
TUBB P07437 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11577171 0.94 CYP1A2 (0.70) CYP1A2CYP2C19CYP3A4CYP2C9TSHR
SCHEMBL12402407 0.91 CYP1A2 (0.79) CYP1A2CYP2C19CYP3A4CYP2C9TSHR
SCHEMBL11805654 0.87 CYP1A2 (0.61) CYP1A2CYP2C19CYP3A4CYP2C9TSHR
SCHEMBL10428893 0.86 ALDH1A1 (0.75) CYP1A2CYP2C19CYP3A4CYP2C9TSHR
SCHEMBL31607627 0.86 ALDH1A1 (0.75) CYP1A2CYP2C19CYP3A4CYP2C9TSHR
SCHEMBL7603587 0.86 HTT (0.66) CYP1A2CYP2C19CYP3A4CYP2C9TSHR
SCHEMBL11814018 0.86 CYP1A2 (0.59) CYP1A2CYP2C19CYP3A4CYP2C9TSHR
SCHEMBL9360017 0.86 CYP1A2 (0.69) CYP1A2CYP2C19CYP3A4CYP2C9TSHR
SCHEMBL15979735 0.84 CTNNB1 (0.62) TSHRLMNAL3MBTL1GAAMAPT
SCHEMBL14700550 0.84 TSHR (0.58) CYP1A2CYP2C19CYP3A4CYP2C9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9142850-B2 Tri-block copolymer and electrolyte membrane made from the same LG CHEM, LTD. (KR) 2015-09-22 US disclosed
US-9048479-B2 Tri-block copolymer and electrolyte membrane made from the same LG CHEM, LTD. (KR) 2015-06-02 US disclosed
US-8986903-B2 Method for producing polymer electrolyte molded article, polymer electrolyte material, polymer electrolyte membrane, and polymer electrolyte fuel cell TORAY INDUSTRIES, INC. (JP) 2015-03-24 US disclosed
US-20140023949-A1 Tri-Block Copolymer and Electrolyte Membrane Made from the Same LG CHEM, LTD. (KR) 2014-01-23 US disclosed
US-20130273450-A1 TRI-BLOCK COPOLYMER AND ELECTROLYTE MEMBRANE MADE FROM THE SAME LG CHEM, LTD. (KR) 2013-10-17 US disclosed
US-8198205-B2 Aromatic block copolymer, decomposition method thereof and analysis method using the decomposition method SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-06-12 US disclosed
US-8178590-B2 Block copolymer and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-05-15 US disclosed
US-20110081597-A1 POLYMER ELECTROLYTE, CROSSLINKED POLYMER ELECTROLYTE, POLYMER ELECTROLYTE MEMBRANE AND USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-07 US disclosed
US-20100239947-A1 Condensed ring-containing polymer electrolyte and application thereof SUMITOMO CHEMICAL COMPANY, LIMITED 2010-09-23 US disclosed
US-20090208806-A1 METHOD FOR PRODUCING POLYMER ELECTROLYTE MOLDED ARTICLE, POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE MEMBRANE, AND POLYMER ELECTROLYTE FUEL CELL TORAY INDUSTRIES, INC. (JP) 2009-08-20 US disclosed
US-20090197763-A1 Aromatic block copolymer, decomposition method thereof and analysis method using the decomposition method SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-08-06 US disclosed
US-20070281195-A1 Block copolymer and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED 2007-12-06 US disclosed
US-7202001-B2 Sulfonated copolymer POLYFUEL, INC. (US) 2007-04-10 US disclosed
US-3983176-A Benzophenones as plant growth regulants NIPPON KAYAKU KABUSHIKI KAISHA (JA) 1976-09-28 US disclosed