Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 3/20 | 0.62 |
| ▸ | WNT3A | P56704 | 3/20 | 0.62 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5495178 | 0.89 | CTNNB1 (0.60) | CTNNB1WNT3ATAS1R3TAS1R1PAX8 | |
| SCHEMBL6339402 | 0.87 | CTNNB1 (0.58) | CTNNB1WNT3ATAS1R3TAS1R1PAX8 | |
| SCHEMBL15979737 | 0.85 | CTNNB1 (0.61) | CTNNB1WNT3APAX8TSHRMAPK1 | |
| SCHEMBL15979670 | 0.84 | CTNNB1 (0.56) | CTNNB1WNT3AMAPTLMNAGAA | |
| SCHEMBL6085421 | 0.84 | CTNNB1 (0.56) | CTNNB1WNT3ATAS1R3TAS1R1MAPT | |
| SCHEMBL9914237 | 0.84 | CYP1A2 (0.63) | TAS1R3TAS1R1MAPTLMNAGAA | |
| SCHEMBL15980084 | 0.83 | LMNA (0.60) | CTNNB1WNT3AMAPTLMNAGAA | |
| SCHEMBL15980081 | 0.83 | CTNNB1 (0.63) | CTNNB1WNT3AL3MBTL1 | |
| SCHEMBL3948073 | 0.83 | MEN1 (0.60) | CTNNB1WNT3ATAS1R3TAS1R1MAPT | |
| SCHEMBL27660341 | 0.83 | CTNNB1 (0.53) | CTNNB1WNT3ATAS1R3TAS1R1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11673885-B2 | γ-diketones as Wnt/β-catenin signaling pathway activators | BIOSPLICE THERAPEUTICS, INC. (US) | 2023-06-13 | — | — | US | disclosed |
| US-9951053-B2 | γ-diketones as Wnt/β-catenin signaling pathway activators | SAMUMED, LLC (US) | 2018-04-24 | — | — | US | disclosed |
| US-20170260176-A1 | GAMMA-DIKETONES AS WNT/BETA -CATENIN SIGNALING PATHWAY ACTIVATORS | MED-PATHWAYS II LIMITED (VG) | 2017-09-14 | — | — | US | disclosed |
| US-9533976-B2 | γ-diketones as WNT/β-catenin signaling pathway activators | SAMUMED, LLC (US) | 2017-01-03 | — | — | US | disclosed |
| US-20140243349-A1 | GAMMA-DIKETONES AS WNT/BETA -CATENIN SIGNALING PATHWAY ACTIVATORS | VICKERS VENTURE FUND VI PTE. LTD. (SG) | 2014-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170260176-A1 | GAMMA-DIKETONES AS WNT/BETA -CATENIN SIGNALING PATHWAY ACTIVATORS | GSK3A, GSK3B, WNT1 | CTNNB1 6/4885WNT3A 4/4885TAS1R3 4142/4885 |
| US-20140243349-A1 | GAMMA-DIKETONES AS WNT/BETA -CATENIN SIGNALING PATHWAY ACTIVATORS | GSK3A, GSK3B, WNT1 | CTNNB1 6/4885WNT3A 4/4885TAS1R3 4142/4885 |
| US-11673885-B2 | γ-diketones as Wnt/β-catenin signaling pathway activators | GSK3A, GSK3B, WNT1 | CTNNB1 5/4885WNT3A 4/4885TAS1R3 4107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.