SCHEMBL9914787

SCHEMBL9914787

O=Cc1cccc(-c2c3ccccc3c(-c3cccc(C=O)c3)c3ccccc23)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.51
TRIM24 O15164 1/20 0.49
TRIM33 Q9UPN9 1/20 0.49
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA9 Q16790 1/20 0.47
ALDH1A1 P00352 3/20 0.47
CYP2A6 P11509 1/20 0.46
AXL P30530 1/20 0.43
KIF11 P52732 2/20 0.43
UNG P13051 1/20 0.42
NPC1 O15118 2/20 0.41
RAB9A P51151 1/20 0.41
CDK8 P49336 1/20 0.41
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
POLB P06746 1/20 0.40
KMT2A Q03164 1/20 0.40
MAOA P21397 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30524232 0.89 ALOX5 (0.47) BRD4TRIM24TRIM33CA12CA1
SCHEMBL12571878 0.89 ALOX5 (0.47) BRD4TRIM24TRIM33CA12CA1
SCHEMBL9914780 0.88 RAB9A (0.44) BRD4TRIM24TRIM33CA12CA1
SCHEMBL9914789 0.87 NPC1 (0.43) BRD4TRIM24TRIM33CA12CA1
SCHEMBL9914781 0.84 TRIM24 (0.48) BRD4TRIM24TRIM33CA12CA1
SCHEMBL9914823 0.83 TRIM24 (0.43) BRD4TRIM24TRIM33CA12CA1
SCHEMBL9914814 0.83 TRIM24 (0.43) BRD4TRIM24TRIM33CA12CA1
SCHEMBL346974 0.82 TRIM24 (0.64) BRD4TRIM24TRIM33CA12CA1
SCHEMBL9914809 0.81 HDAC4 (0.42) BRD4TRIM24TRIM33CA12CA1
SCHEMBL97618 0.80 TRIM24 (0.69) BRD4TRIM24TRIM33CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8197951-B2 Emitting material and organic light emitting diode using the same LG CHEM, LTD. (KR) 2012-06-12 US disclosed
US-8197951-B2 Emitting material and organic light emitting diode using the same LG CHEM, LTD. (KR) 2012-06-12 US disclosed
US-20070202355-A1 Emitting material and organic light emitting diode using the same LG CHEM. LTD. (KR) 2007-08-30 US disclosed
US-20070202355-A1 Emitting material and organic light emitting diode using the same LG CHEM. LTD. (KR) 2007-08-30 US disclosed