Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24786351 | 0.90 | GAA (0.49) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL30843763 | 0.90 | GAA (0.53) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL9915146 | 0.89 | KMT2A (0.42) | ALDH1A1LMNAGLAKMT2A | |
| SCHEMBL10131064 | 0.86 | GAA (0.50) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL14755268 | 0.83 | CYP26A1 (0.58) | GAARAB9AALDH1A1L3MBTL1CYP26A1 | |
| SCHEMBL15281190 | 0.83 | ESRRB (0.47) | GAAALDH1A1LMNAGLAL3MBTL1 | |
| SCHEMBL10131060 | 0.79 | CYP26A1 (0.51) | GAARAB9AALDH1A1CYP26A1CTSL | |
| SCHEMBL3679721 | 0.78 | RAB9A (0.59) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL5672076 | 0.78 | GAA (0.56) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL10024019 | 0.78 | GAA (0.56) | GAARAB9AALDH1A1LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012075242-A2 | CONTROLLED CHEMICAL RELEASE OF HYDROGEN SULFIDE | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-06-07 | — | — | WO | disclosed |