Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.51 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5672076 | 1.00 | GAA (0.56) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL9925857 | 0.94 | ALDH1A1 (0.56) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL26199837 | 0.87 | CYP26A1 (0.53) | GAARAB9AALDH1A1CYP26A1GPR139 | |
| SCHEMBL27673425 | 0.87 | CYP26A1 (0.53) | GAARAB9AALDH1A1CYP26A1GPR139 | |
| SCHEMBL3679721 | 0.87 | RAB9A (0.59) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL23967346 | 0.85 | GAA (0.54) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL7448811 | 0.85 | GAA (0.54) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL7448810 | 0.85 | GAA (0.54) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL8235468 | 0.85 | CA1 (0.56) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL13885653 | 0.85 | LNPEP (0.56) | GAARAB9ATAS1R3TAS1R1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130008-A2 | PHARMACEUTICAL COMPOSITIONS OF 6-(2-(2H-TETRAZOL-5-YL)ETHYL)DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID AND DERIVATIVES THEREOF | SEA PHARMACEUTICALS LLC (US) | 2023-07-06 | — | — | WO | disclosed |
| EP-2957555-A1 | METHOD FOR MODIFYING DERIVATIVES OF AMINO ACIDS AND PEPTIDES, COMPOUNDS PRODUCED, AND USE | Consejo Superior De Investigaciones Científicas (CSIC) (ES) | 2015-12-23 | — | — | EP | disclosed |
| WO-2014125145-A1 | METHOD FOR MODIFYING DERIVATIVES OF AMINO ACIDS AND PEPTIDES, COMPOUNDS PRODUCED, AND USE | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) | 2014-08-21 | — | — | WO | disclosed |
| WO-2013001120-A1 | CHEMICAL PROCESS FOR THE SELECTIVE MODIFICATION OF PEPTIDES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) | 2013-01-03 | — | — | WO | disclosed |
| WO-2012017114-A1 | METHOD FOR OBTAINING AZETIDINE DERIVATIVES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) | 2012-02-09 | — | — | WO | disclosed |