SCHEMBL9915339

SCHEMBL9915339

c1ccc(-c2ccc(C(c3ccccc3)C3CCCN3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 8/20 0.47
SLC6A2 P23975 6/20 0.47
SLC6A4 P31645 5/20 0.47
DHFR P00374 1/20 0.43
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
TSHR P16473 1/20 0.43
TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12996843 1.00 SLC6A3 (0.47) SLC6A3SLC6A2SLC6A4DHFRALDH1A1
SCHEMBL10326440 0.98 SLC6A3 (0.47) SLC6A3SLC6A2SLC6A4DHFR
SCHEMBL10326717 0.98 SLC6A3 (0.47) SLC6A3SLC6A2SLC6A4DHFR
SCHEMBL10326261 0.98 SLC6A3 (0.47) SLC6A3SLC6A2SLC6A4DHFR
SCHEMBL10326624 0.93 SLC6A3 (0.54) SLC6A3SLC6A2SLC6A4DHFRALDH1A1
SCHEMBL10327324 0.93 SLC6A3 (0.54) SLC6A3SLC6A2SLC6A4DHFRALDH1A1
SCHEMBL10326911 0.93 SLC6A3 (0.54) SLC6A3SLC6A2SLC6A4DHFRALDH1A1
SCHEMBL670331 0.91 SLC6A3 (0.53) SLC6A3SLC6A2SLC6A4DHFRALDH1A1
SCHEMBL2844473 0.91 SLC6A3 (0.53) SLC6A3SLC6A2SLC6A4DHFRALDH1A1
SCHEMBL2842321 0.91 SLC6A3 (0.53) SLC6A3SLC6A2SLC6A4DHFRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012074075-A1 METHOD FOR MANUFACTURING OPTICALLY ACTIVE MENTHOL 高砂香料工業株式会社 (JP) 2012-06-07 WO disclosed
WO-2011108672-A2 HOMOGENEOUS ASYMMETRIC HYDROGENATION CATALYST 高砂香料工業株式会社 (JP) 2011-09-09 WO disclosed